Chinese Silkvine (Periploca sepium), known as "Xiang Jia Pi" in traditional Chinese medicine (TCM), has been used historically for its various medicinal properties, including the treatment of rheumatic conditions, edema, and pain. Its use for hemorrhoids is based primarily on traditional practices rather than robust scientific evidence. In TCM, herbs like Chinese Silkvine are believed to promote blood circulation, reduce swelling, and relieve pain, which aligns with the symptomatic management of hemorrhoids. Historical texts and some TCM compendiums mention the use of Chinese Silkvine in formulations intended to address swelling and pain associated with hemorrhoids, often in combination with other herbs.

However, modern pharmacological or clinical studies specifically evaluating the effectiveness of Chinese Silkvine for hemorrhoids are lacking. Most available research on the plant pertains to its anti-inflammatory, analgesic, and immunomodulatory effects, but these studies are generally not targeted at hemorrhoidal disease. Therefore, while there is a tradition of using Chinese Silkvine for hemorrhoids, the scientific evidence supporting this application remains weak. Practitioners who use the herb for this purpose do so based on centuries-old practices rather than contemporary clinical validation.