Evidence supporting the use of: Escin
For the health condition: Hemorrhoids

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Escin, a natural mixture of triterpene saponins derived from horse chestnut (Aesculus hippocastanum), is used in the support and treatment of hemorrhoids primarily due to its anti-inflammatory, vasoprotective, and anti-edematous effects. Several clinical studies and reviews have examined the efficacy of escin for chronic venous insufficiency and related vascular conditions, which include hemorrhoids. Escin is believed to reduce capillary permeability, strengthen vascular walls, and decrease swelling, which are beneficial in managing the symptoms of hemorrhoids such as pain, edema, and inflammation.

Randomized controlled trials and meta-analyses (e.g., Pittler & Ernst, 2012; Sirtori, 2001) have found that oral and topical escin preparations can reduce symptoms of venous insufficiency and may provide symptomatic relief for hemorrhoids. While not as extensively studied as some pharmaceutical agents, the evidence for escin is stronger than many other herbal remedies, with several double-blind trials supporting its use for vascular disorders. However, the number of high-quality, hemorrhoid-specific trials is still limited, and most recommendations are extrapolated from studies on chronic venous insufficiency and edema.

Overall, escin’s use for hemorrhoids is supported by a combination of pharmacological rationale and moderate clinical evidence, justifying its inclusion in some treatment protocols. Nevertheless, more robust, targeted research is needed to confirm its efficacy and safety specifically for hemorrhoidal disease.

More about escin
More about Hemorrhoids

Other ingredients used for Hemorrhoids

Abrus
Acacia
Achyranthes
Aconite
Aerva lanata
Aescin
Agrimonia pilosa
Agrimony
Ajuga
Alchemilla
Allicin
Allium tuberosum
Aloe vera
American Liverleaf
Amor seco
Angelica
anthocyanidins
anthraquinone
Antirrhinum majus
antler
apple
apple cider vinegar
apricot
Ardisia
aster root
avens
bael
Baliospermum
banyan
Barleria
Bassia scoparia
bayleaf
Bergenia
betel
bilberry
bioflavonoids
birch
Black Hellebore
black nightshade
black root
blackberry
blackboard tree
Blepharis
Borassus aethiopum
borassus palm
bran
Brassica
butcher's broom
cabbage
cactus
Caesalpinia crista
capsicum
Carthamus
castor oil
Celosia
chamomile
chard
chestnut
Chinese silkvine
Chondrus
cinquefoil
citrus bioflavonoids
Clerodendrum indicum
coconut oil
colocynth
commiphora
Cucurbita
Cyathula
Cynodon dactylon
dandelion
Dianthus
Diosmin
elephant\'s head
Embelia
escin
fiber
fiber blend (proprietary)
Ficus simplicissima
geranium
gotu kola
green chiretta
hazelnut
horse chestnut
Indian coraltree
Kokilaksha
labrador tea
lemon
lichen
licorice root
little ironweed
Lycopodium
Methylcellulose
Mezoneuron benthamianum
Morinda
Morning glory
Morus
Mountain Pepper
Mucilage
Myrrh
Nettle
Nimbidin
Nymphaea nouchali
Oak
Oligomeric proanthocyanidins
Onosma bracteatum
oregon grape
Oroxylum indicum
pagoda tree
Papayotin
parsley
paw paw
Pentacyclic triterpenoids
peony
Persimmon
phellodendron amurense
Pluchea
plum fruit
Polygonum
Portulaca
proanthocyanidins
prune
Prunus
psyllium
punarnava
rhubarb
Rosa laevigata
Rosabin
Rubia cordifolia
Ruscogenins
Ruscus
rutin
Rutosides
Sanguisorba
Sarivan
sea salt
seaweed
Shark Liver Oil
shepherd's purse
slippery elm bark
Sumac
Sword Bean
Szechuan lovage
Tamarind
Tannins
Taraxacin
Terminalia
Triphala
Troxerutin
turmeric
Varuna
vitamin C
Wax Gourd
Winter Begonia
Witch Hazel
Yellow Dock
Zinc
Zucchini

Products containing escin

We currently have no products on Vitabase that contain this ingredient.