Evidence supporting the use of: Escin
For the health condition: Hemorrhoids
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Escin, a natural mixture of triterpene saponins derived from horse chestnut (Aesculus hippocastanum), is used in the support and treatment of hemorrhoids primarily due to its anti-inflammatory, vasoprotective, and anti-edematous effects. Several clinical studies and reviews have examined the efficacy of escin for chronic venous insufficiency and related vascular conditions, which include hemorrhoids. Escin is believed to reduce capillary permeability, strengthen vascular walls, and decrease swelling, which are beneficial in managing the symptoms of hemorrhoids such as pain, edema, and inflammation.
Randomized controlled trials and meta-analyses (e.g., Pittler & Ernst, 2012; Sirtori, 2001) have found that oral and topical escin preparations can reduce symptoms of venous insufficiency and may provide symptomatic relief for hemorrhoids. While not as extensively studied as some pharmaceutical agents, the evidence for escin is stronger than many other herbal remedies, with several double-blind trials supporting its use for vascular disorders. However, the number of high-quality, hemorrhoid-specific trials is still limited, and most recommendations are extrapolated from studies on chronic venous insufficiency and edema.
Overall, escin’s use for hemorrhoids is supported by a combination of pharmacological rationale and moderate clinical evidence, justifying its inclusion in some treatment protocols. Nevertheless, more robust, targeted research is needed to confirm its efficacy and safety specifically for hemorrhoidal disease.
Other ingredients used for Hemorrhoids
Aloe veragreen chiretta
apple
apricot
berry flavor
betel
bilberry
blackberry
butcher's broom
chamomile
citrus bioflavonoids
turmeric
dandelion
fiber blend (proprietary)
gotu kola
cellulose
horse chestnut
lemon
licorice root
Nettle
oregon grape
parsley
phellodendron amurense
plum fruit
prune
psyllium
rutin
slippery elm bark
Triphala
vitamin C
seaweed
Zinc
tangerine
capsicum
punarnava
commiphora
blackboard tree
Caesalpinia crista
Rubia cordifolia
peony
Szechuan lovage
Morus
Myrrh
Morinda
birch
aster root
shepherd's purse
paw paw
geranium
sea salt
avens
apple cider vinegar
antler
anthraquinone
Ardisia
Angelica
Acacia
Agrimony
Allicin
Antirrhinum majus
Achyranthes
Abrus
Alchemilla
Aconite
Ajuga
Aerva lanata
American Liverleaf
Aescin
anthocyanidins
Agrimonia pilosa
Allium tuberosum
Amor seco
Baliospermum
Blepharis
Brassica
bayleaf
bran
Barleria
bael
banyan
bioflavonoids
back nightshade
borassus palm
Borassus aethiopum
black root
Bassia scoparia
Black Hellebore
Bergenia
Chinese silkvine
Cucurbita
coconut oil
cactus
cinquefoil
Cyathula
chard
cabbage
chestnut
Cynodon dactylon
castor oil
Carthamus
colocynth
Celosia
Clerodendrum indicum
Chondrus
Dianthus
Diosmin
elephant\'s head
escin
Embelia
fiber
Ficus simplicissima
hazelnut
Indian coraltree
Kokilaksha
lichen
Lycopodium
labrador tea
little ironweed
Methylcellulose
Mezoneuron benthamianum
Mountain Pepper
Mucilage
Morning glory
Nymphaea nouchali
Nimbidin
Oak
Oroxylum indicum
Oligomeric proanthocyanidins
Onosma bracteatum
pagoda tree
Pluchea
potato
Prunus
Pentacyclic triterpenoids
proanthocyanidins
Portulaca
Persimmon
Papayotin
Polygonum
Rosabin
Ruscus
Ruscogenins
Rosa laevigata
Rutosides
rhubarb
Shark Liver Oil
Sanguisorba
Sarivan
Squash
Sumac
Sword Bean
Terminalia
Tannins
Taraxacin
Troxerutin
Tamarind
Varuna
Wax Gourd
Witch Hazel
Winter Begonia
Yellow Dock
Zucchini
Other health conditions supported by escin
Bruises (healing)Edema
Hemorrhoids
Inflammation
Phlebitis
Spider Veins
Thrombosis
Varicose Veins
Wounds and Sores