Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Hesperidin methylchalcone is a semi-synthetic derivative of hesperidin, a flavonoid found in citrus fruits. There is scientific evidence supporting its use in the treatment and support of hemorrhoids, although the strength of this evidence is moderate rather than definitive. Hesperidin methylchalcone is commonly included in phlebotropic medications, often in combination with other flavonoids such as diosmin and rutin. These compounds are believed to strengthen capillaries, reduce vascular permeability, and exhibit anti-inflammatory effects.

Several randomized controlled trials and meta-analyses have evaluated the efficacy of micronized purified flavonoid fractions (MPFF), which frequently contain hesperidin methylchalcone, in the treatment of hemorrhoidal disease. Clinical studies suggest that these preparations can reduce symptoms such as bleeding, pain, and swelling, and may accelerate symptom resolution, especially during acute attacks. The mechanism is thought to involve improvement of venous tone, lymphatic drainage, and reduction of inflammation.

However, while the overall data are consistent with a benefit, many studies use combination products, making it difficult to attribute the effect solely to hesperidin methylchalcone. Furthermore, the quality of some studies is variable, and there is a need for more high-quality, hesperidin methylchalcone-specific trials. Nevertheless, its inclusion in evidence-based guidelines (such as those from the American Society of Colon and Rectal Surgeons) supports its use as a symptomatic treatment for hemorrhoids.

More about Hesperidin methylchalcone
More about Hemorrhoids

Other ingredients used for Hemorrhoids

Aloe vera
green chiretta
apple
apricot
berry flavor
betel
bilberry
blackberry
butcher's broom
chamomile
citrus bioflavonoids
turmeric
dandelion
fiber blend (proprietary)
gotu kola
cellulose
horse chestnut
lemon
licorice root
Nettle
oregon grape
parsley
phellodendron amurense
plum fruit
prune
psyllium
rutin
slippery elm bark
Triphala
vitamin C
seaweed
Zinc
capsicum
punarnava
commiphora
blackboard tree
Caesalpinia crista
Rubia cordifolia
peony
Szechuan lovage
Morus
Myrrh
Morinda
birch
aster root
shepherd's purse
paw paw
geranium
sea salt
avens
apple cider vinegar
antler
anthraquinone
Ardisia
Angelica
Acacia
Agrimony
Allicin
Antirrhinum majus
Achyranthes
Abrus
Alchemilla
Aconite
Ajuga
Aerva lanata
American Liverleaf
Aescin
anthocyanidins
Agrimonia pilosa
Allium tuberosum
Amor seco
Baliospermum
Blepharis
Brassica
bayleaf
bran
Barleria
bael
banyan
bioflavonoids
black nightshade
borassus palm
Borassus aethiopum
black root
Bassia scoparia
Black Hellebore
Bergenia
Chinese silkvine
Cucurbita
coconut oil
cactus
cinquefoil
Cyathula
chard
cabbage
chestnut
Cynodon dactylon
castor oil
Carthamus
colocynth
Celosia
Clerodendrum indicum
Chondrus
Dianthus
Diosmin
elephant\'s head
escin
Embelia
fiber
Ficus simplicissima
hazelnut
Indian coraltree
Kokilaksha
lichen
Lycopodium
labrador tea
little ironweed
Methylcellulose
Mezoneuron benthamianum
Mountain Pepper
Mucilage
Morning glory
Nymphaea nouchali
Nimbidin
Oak
Oroxylum indicum
Oligomeric proanthocyanidins
Onosma bracteatum
pagoda tree
Pluchea
Prunus
Pentacyclic triterpenoids
proanthocyanidins
Portulaca
Persimmon
Papayotin
Polygonum
Rosabin
Ruscus
Ruscogenins
Rosa laevigata
Rutosides
rhubarb
Shark Liver Oil
Sanguisorba
Sarivan
Sumac
Sword Bean
Terminalia
Tannins
Taraxacin
Troxerutin
Tamarind
Varuna
Wax Gourd
Witch Hazel
Winter Begonia
Yellow Dock
Zucchini

Other health conditions supported by Hesperidin methylchalcone

Capillary Weakness
Circulation (poor)
Edema
Hemorrhoids
Inflammation
Phlebitis
Spider Veins
Varicose Veins

Products containing Hesperidin methylchalcone

We currently have no products on Vitabase that contain this ingredient.