Evidence supporting the use of: Hydroxyanthracene derivative
For the health condition: Hemorrhoids

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Hydroxyanthracene derivatives (HADs), such as those found in senna, cascara, and aloe, have a long history of use as stimulant laxatives in traditional medicine. The rationale for their use in hemorrhoid management is based primarily on their ability to soften stools and promote bowel movements, thereby reducing straining during defecation—a common aggravating factor for hemorrhoids. Historically, herbal preparations containing HADs have been recommended in folk medicine to help alleviate constipation, indirectly supporting hemorrhoid symptom relief by minimizing trauma to the anal region. However, scientific evidence directly supporting the efficacy or safety of hydroxyanthracene derivatives specifically for treating or supporting hemorrhoids is limited and of low quality. Most clinical studies and regulatory evaluations focus on their laxative effects rather than any direct anti-hemorrhoidal properties. Some guidelines caution against routine use of stimulant laxatives due to potential side effects, such as cramping, dependency, or electrolyte imbalance, particularly with prolonged use. Overall, the use of hydroxyanthracene derivatives in hemorrhoid management is primarily justified by tradition, with only indirect and low-level evidence supporting their benefit via stool softening and constipation relief.

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Other health conditions supported by Hydroxyanthracene derivative

Colon (atonic)
Colon (spastic)
Constipation (adults)
Hemorrhoids
Irritable Bowel Syndrome

Products containing Hydroxyanthracene derivative

We currently have no products on Vitabase that contain this ingredient.