Evidence supporting the use of: Rutosides
For the health condition: Hemorrhoids

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Rutosides, also known as rutin, are flavonoid compounds found in various plants, most notably in buckwheat and certain fruits. They have been used in the management of hemorrhoids primarily due to their purported effects in strengthening capillary walls, reducing capillary permeability, and exhibiting anti-inflammatory properties. Several clinical studies and reviews have investigated the use of rutosides, especially in combination with other flavonoids (such as diosmin and hesperidin), for the treatment of chronic venous insufficiency and hemorrhoids.

A number of randomized controlled trials and meta-analyses have shown that micronized purified flavonoid fractions, which include rutosides, can reduce symptoms such as bleeding, pain, and swelling associated with hemorrhoids. The most robust evidence comes from studies of combination preparations (e.g., diosmin, hesperidin, and rutosides), so the specific contribution of rutosides alone is less clear. However, rutosides are thought to contribute to the overall effect due to their ability to reduce inflammation and improve venous tone.

International guidelines, such as those from the American Society of Colon and Rectal Surgeons, acknowledge the use of flavonoid mixtures as an adjunct in the management of symptomatic hemorrhoids, though they do not specifically single out rutosides. The evidence is moderate (rated here as 3 out of 5), as most studies involve combination products and there is a lack of large, high-quality trials examining rutosides alone.

More about Rutosides
More about Hemorrhoids

Other ingredients used for Hemorrhoids

Abrus
Acacia
Achyranthes
Aconite
Aerva lanata
Aescin
Agrimonia pilosa
Agrimony
Ajuga
Alchemilla
Allicin
Allium tuberosum
Aloe vera
American Liverleaf
Amor seco
Angelica
anthocyanidins
anthraquinone
Antirrhinum majus
antler
apple
apple cider vinegar
apricot
Ardisia
aster root
avens
bael
Baliospermum
banyan
Barleria
Bassia scoparia
bayleaf
Bergenia
betel
bilberry
bioflavonoids
birch
Black Hellebore
black nightshade
black root
blackberry
blackboard tree
Blepharis
Borassus aethiopum
borassus palm
bran
Brassica
butcher's broom
cabbage
cactus
Caesalpinia crista
capsicum
Carthamus
castor oil
Celosia
chamomile
chard
chestnut
Chinese silkvine
Chondrus
cinquefoil
citrus bioflavonoids
Clerodendrum indicum
coconut oil
colocynth
commiphora
Cucurbita
Cyathula
Cynodon dactylon
dandelion
Dianthus
Diosmin
elephant\'s head
Embelia
escin
fiber
fiber blend (proprietary)
Ficus simplicissima
geranium
gotu kola
green chiretta
hazelnut
horse chestnut
Indian coraltree
Kokilaksha
labrador tea
lemon
lichen
licorice root
little ironweed
Lycopodium
Methylcellulose
Mezoneuron benthamianum
Morinda
Morning glory
Morus
Mountain Pepper
Mucilage
Myrrh
Nettle
Nimbidin
Nymphaea nouchali
Oak
Oligomeric proanthocyanidins
Onosma bracteatum
oregon grape
Oroxylum indicum
pagoda tree
Papayotin
parsley
paw paw
Pentacyclic triterpenoids
peony
Persimmon
phellodendron amurense
Pluchea
plum fruit
Polygonum
Portulaca
proanthocyanidins
prune
Prunus
psyllium
punarnava
rhubarb
Rosa laevigata
Rosabin
Rubia cordifolia
Ruscogenins
Ruscus
rutin
Rutosides
Sanguisorba
Sarivan
sea salt
seaweed
Shark Liver Oil
shepherd's purse
slippery elm bark
Sumac
Sword Bean
Szechuan lovage
Tamarind
Tannins
Taraxacin
Terminalia
Triphala
Troxerutin
turmeric
Varuna
vitamin C
Wax Gourd
Winter Begonia
Witch Hazel
Yellow Dock
Zinc
Zucchini

Products containing Rutosides

We currently have no products on Vitabase that contain this ingredient.