Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Alpha-Lipoic Acid (ALA) has some scientific support for its use in supporting the hepatic (liver) system, particularly in the context of liver diseases such as non-alcoholic fatty liver disease (NAFLD), alcoholic liver disease, and drug-induced liver injury. ALA is a potent antioxidant that can scavenge free radicals and regenerate other antioxidants, such as vitamins C and E. Several animal and human studies suggest that ALA may reduce oxidative stress and inflammation in the liver, which are central mechanisms involved in various liver disorders.

Clinical trials have demonstrated that ALA supplementation can improve liver enzyme levels (such as ALT and AST) and reduce markers of oxidative stress in patients with NAFLD and other liver conditions. Some studies have also shown that ALA may help mitigate hepatotoxicity caused by toxins or medications, such as acetaminophen or chemotherapy drugs. However, while these findings are promising, the overall body of evidence is moderate, with some studies being small in size or of limited duration. Larger, high-quality randomized controlled trials are still needed to confirm efficacy, determine optimal dosing, and assess long-term safety.

In summary, there is reasonable scientific rationale and some clinical evidence supporting the use of Alpha-Lipoic Acid for liver support, but it should not replace established therapies for liver diseases. Its role is best seen as adjunctive, and patients should consult healthcare professionals before starting supplementation.

More about Alpha-Lipoic Acid
More about Hepatic System

Other ingredients that support Hepatic System

amino acids
artichoke
barberry
berberine
black garlic
bovine
bovine liver
broccoli
bupleurum falcatum
turmeric
curcumin
d-glucarate
dandelion
epigallocatechin gallate (EGCG)
fructose
garlic bulb
gentian root
gooseberry
green tea
hesperetin
kale
L-glutathione
L-methionine
L-Ornithine
lecithin
liquid liver fractions
matcha
milk thistle
n-acetyl-cysteine (NAC)
naringin
niacin (vitamin B3)
niacinamide (Vitamin B3)
nicotinamide riboside
oleanolic acid
olive
ox bile
pantethine
parsley
phenolic compounds
phosphatidylcholine
phospholipids
pumpkin
riboflavin (vitamin B2)
schisandra chinensis
silymarin
sulforaphane glucosinolate
tocotrienols
trimethylglycine (TMG)
triphala
vitamin B
water
watercress
zinc
jiaogulan
punarnava
picrorhiza kurroa
lingzhi
bile salt
ferulic acid
ganoderma
polyphenols
trace minerals
herbal blend (proprietary)
Algae
AMP-activated protein kinase (AMPK)
Apigenin
Antrodia camphorata
Arginine carglumate
AHCC
Andrographolide
Alpha-Lipoic Acid
Ampelopsin
Animal protein
Black Seed
Borotutu
Brassica
Beef liver
Baicalein
Basidiomycota
boldo
Betanin
berry
Bitter principals
bile acid
Bupleurum
Boerhavia diffusa
cholic acid
Carqueja
Catalpol
Coenzyme A
Capillary Artemisia
chlorogenic acid
Curcuminoid
Cynarin
Cruciferous
Capers
Chanca Piedra
Curcuma
Chinese Thoroughwax
Corilagin
Cynaropicrin
Dihydromyricetin
DL-Methionine
Dehydrocholic acid
Dihydrolipoic Acid
Dithiolthiones
Eriocitrin
Egg
Eclipta
Emblicanin
Fungus
Fringetree
Flavonolignan
Ginsenosides
Gypenoside
Gamma-Glutamylcysteine
Gallate
glucose
Glycocholic acid
Glycyrrhetinic Acid
Guggulsterones
Glycyrrhizin
Gentiana manshurica
Glycochenodeoxycholic acid
Isosilybin
isoliquiritigenin
Jurubeba
Kutkins
Maslinic Acid
Mangiferin
Monoterpenes
Myricetin
Mushroom
Naringenin
Nigella Seed
Nobiletin
Oxymatrine
Ornithine l-aspartic acid
Phyllanthus
Puerarin
Phenylpropanoids
Picroside
Pentacyclic triterpenoids
Polydatin
Phthalides
Pu-Er Tea
Polymethoxylated flavones
Plukenetia volubilis
Scoparia dulcis
Silybin
Salvianolic acid
Schisandrins
Silydianin
Silychristin
Schizandrol A
Silybum
S-allylcysteine
Sesamin
Sulforaphane
Terminalia
Terpenoids
Thymoquinone
Taxifolin
Thistle
Taurochenodeoxycholic acid
Taurocholic acid
Triterpenes
Taurodeoxycholic acid
Taraxacum
Theabrownin
Wogonin
Xanthohumol
Xanthorrhizol
Yin Chen

Other body systems supported by Alpha-Lipoic Acid

Arteries
Blood
Brain
Circulatory System
Heart
Hepatic System
Liver
Mitochondria
Nerves
Skin

Products containing Alpha-Lipoic Acid

We currently have no products on Vitabase that contain this ingredient.