Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Catalpol is an iridoid glycoside compound primarily found in the root of Rehmannia glutinosa, a herb widely used in Traditional Chinese Medicine (TCM). In TCM, Rehmannia is frequently prescribed for its perceived benefits to the liver (hepatic system), including claims of "nourishing yin" and "cooling the blood," which are thought to support liver function and protect against liver disorders. However, direct scientific studies on catalpol for hepatic support are limited. Some in vivo studies in animal models suggest that catalpol may exhibit hepatoprotective effects, such as reducing liver inflammation and oxidative stress induced by toxins. For example, a few rodent studies have shown that catalpol administration can decrease markers of liver injury (such as alanine aminotransferase and aspartate aminotransferase) and reduce histopathological damage in chemically-induced liver injury models. Despite these findings, clinical evidence in humans is lacking, and most support for catalpol’s use in liver health is derived from its traditional use in herbal formulations rather than robust clinical validation. Therefore, the use of catalpol to support the hepatic system is justified primarily by tradition, with only limited preclinical scientific evidence available and no substantial clinical trials to date.

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mangiferin
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Other body systems supported by catalpol

Brain
Circulatory System
Heart
Hepatic System
Immune System
Intestinal System
Kidneys
Liver
Nerves

Products containing catalpol

We currently have no products on Vitabase that contain this ingredient.