Curcuma, most commonly referring to Curcuma longa (turmeric), has a long history of use in traditional medicine systems such as Ayurveda and Traditional Chinese Medicine for supporting liver health and overall hepatic function. Modern scientific research has increasingly investigated curcumin, the primary active compound in turmeric, for its hepatoprotective properties. Numerous preclinical studies in animal models have demonstrated that curcumin can protect the liver from various toxins, reduce hepatic inflammation, and ameliorate oxidative stress. Curcumin exhibits antioxidant and anti-inflammatory effects, which play a crucial role in reducing liver injury and fibrosis.

Human clinical studies, while more limited in number, have provided some supportive evidence as well. Small-scale clinical trials have shown that turmeric supplementation may help reduce liver enzyme levels in individuals with nonalcoholic fatty liver disease (NAFLD) and improve markers of oxidative stress. However, issues such as curcumin's low bioavailability and the variability in supplement formulations mean that standardized dosing and long-term safety are still being researched. Despite these limitations, the combination of traditional use and a growing body of scientific evidence indicates that Curcuma does have a supportive role in hepatic system health, justifying its widespread use for this purpose.