Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Cynaropicrin is a sesquiterpene lactone found predominantly in artichoke (Cynara scolymus). Its use to support the hepatic (liver) system is supported by a growing body of scientific evidence, primarily from animal and in vitro studies. Research has demonstrated that cynaropicrin possesses hepatoprotective properties. For instance, studies have shown that cynaropicrin can mitigate liver damage induced by chemicals such as carbon tetrachloride (CCl₄) and acetaminophen in animal models, likely due to its antioxidant and anti-inflammatory effects. It appears to modulate pathways associated with oxidative stress and inflammation, both of which are critical in the pathophysiology of liver injury. Additionally, cynaropicrin has been reported to inhibit the activation of hepatic stellate cells, which play a central role in the development of liver fibrosis.

Despite these promising findings in preclinical research, there is currently a lack of robust clinical data in humans to confirm the efficacy and safety of cynaropicrin for hepatic support. Traditional medicine systems have used artichoke extracts (which contain cynaropicrin) for liver health, but the use of isolated cynaropicrin is based on scientific investigation rather than tradition. Therefore, while the scientific rationale exists, more well-designed human studies are needed before cynaropicrin can be firmly recommended for hepatic support.

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Other ingredients that support Hepatic System

amino acids
artichoke
barberry
berberine
black garlic
bovine
bovine liver
broccoli
bupleurum falcatum
turmeric
curcumin
d-glucarate
dandelion
epigallocatechin gallate (EGCG)
fructose
garlic bulb
gentian root
gooseberry
green tea
hesperetin
kale
L-glutathione
L-methionine
L-Ornithine
lecithin
liquid liver fractions
matcha
milk thistle
n-acetyl-cysteine (NAC)
naringin
niacin (vitamin B3)
niacinamide (Vitamin B3)
nicotinamide riboside
oleanolic acid
olive
ox bile
pantethine
parsley
phenolic compounds
phosphatidylcholine
phospholipids
pumpkin
riboflavin (vitamin B2)
schisandra chinensis
silymarin
sulforaphane glucosinolate
tocotrienols
trimethylglycine (TMG)
triphala
vitamin B
water
watercress
zinc
jiaogulan
punarnava
picrorhiza kurroa
lingzhi
bile salt
ferulic acid
ganoderma
polyphenols
trace minerals
herbal blend (proprietary)
Algae
AMP-activated protein kinase (AMPK)
Apigenin
Antrodia camphorata
Arginine carglumate
AHCC
Andrographolide
Alpha-Lipoic Acid
Ampelopsin
Animal protein
Black Seed
Borotutu
Brassica
Beef liver
Baicalein
Basidiomycota
boldo
Betanin
berry
Bitter principals
bile acid
Bupleurum
Boerhavia diffusa
cholic acid
Carqueja
Catalpol
Coenzyme A
Capillary Artemisia
chlorogenic acid
Curcuminoid
Cynarin
Cruciferous
Capers
Chanca Piedra
Curcuma
Chinese Thoroughwax
Corilagin
Cynaropicrin
Dihydromyricetin
DL-Methionine
Dehydrocholic acid
Dihydrolipoic Acid
Dithiolthiones
Eriocitrin
Egg
Eclipta
Emblicanin
Fungus
Fringetree
Flavonolignan
Ginsenosides
Gypenoside
Gamma-Glutamylcysteine
Gallate
glucose
Glycocholic acid
Glycyrrhetinic Acid
Guggulsterones
Glycyrrhizin
Gentiana manshurica
Glycochenodeoxycholic acid
Isosilybin
isoliquiritigenin
Jurubeba
Kutkins
Maslinic Acid
Mangiferin
Monoterpenes
Myricetin
Mushroom
Naringenin
Nigella Seed
Nobiletin
Oxymatrine
Ornithine l-aspartic acid
Phyllanthus
Puerarin
Phenylpropanoids
Picroside
Pentacyclic triterpenoids
Polydatin
Phthalides
Pu-Er Tea
Polymethoxylated flavones
Plukenetia volubilis
Scoparia dulcis
Silybin
Salvianolic acid
Schisandrins
Silydianin
Silychristin
Schizandrol A
Silybum
S-allylcysteine
Sesamin
Sulforaphane
Terminalia
Terpenoids
Thymoquinone
Taxifolin
Thistle
Taurochenodeoxycholic acid
Taurocholic acid
Triterpenes
Taurodeoxycholic acid
Taraxacum
Theabrownin
Wogonin
Xanthohumol
Xanthorrhizol
Yin Chen

Other body systems supported by Cynaropicrin

Digestive System
Gastrointestinal Tract
Hepatic System
Liver

Products containing Cynaropicrin

We currently have no products on Vitabase that contain this ingredient.