Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Dihydrolipoic Acid (DHLA) is the reduced, active form of alpha-lipoic acid (ALA), an endogenous compound with antioxidant properties. ALA and DHLA have been investigated for their roles in hepatic (liver) health, primarily due to their ability to scavenge reactive oxygen species and regenerate other antioxidants such as glutathione. Some preclinical and limited clinical studies suggest that ALA and its reduced form DHLA may help protect liver cells from oxidative damage, attenuate inflammation, and improve liver function in certain conditions such as non-alcoholic fatty liver disease (NAFLD) and drug-induced hepatotoxicity. However, most of the available data relate to ALA rather than DHLA specifically, and the majority of evidence comes from in vitro studies or animal models, with relatively few high-quality, large-scale clinical trials in humans directly assessing DHLA’s effects on liver health. As a result, while the biochemical rationale for DHLA use in supporting hepatic function exists, the direct scientific validation in humans is limited. Therefore, the use of DHLA for hepatic support is backed by some scientific evidence, but overall, the clinical evidence is modest and more research is needed to firmly establish its efficacy for liver health.

More about dihydrolipoic acid
More about Hepatic System

Other ingredients that support Hepatic System

AHCC
Algae
alpha-lipoic acid
amino acids
AMP-activated protein kinase (AMPK)
ampelopsin
andrographolide
animal protein
Antrodia camphorata
apigenin
Arginine carglumate
artichoke
baicalein
barberry
Basidiomycota
Beef liver
berberine
berry
betanin
bile acid
bile salt
bitter principals
black garlic
black seed
Boerhavia diffusa
boldo
borotutu
bovine
bovine liver
Brassica
broccoli
Bupleurum
bupleurum falcatum
capers
capillary artemisia
carqueja
catalpol
chanca piedra
Chinese thoroughwax
chlorogenic acid
cholic acid
Coenzyme A
corilagin
cruciferous
Curcuma
curcumin
Curcuminoid
cynarin
cynaropicrin
d-glucarate
dandelion
dehydrocholic acid
dihydrolipoic acid
dihydromyricetin
dithiolthiones
DL-Methionine
Eclipta
egg
emblicanin
epigallocatechin gallate (EGCG)
eriocitrin
ferulic acid
flavonolignan
fringetree
fungus
gallate
gamma-glutamylcysteine
ganoderma
garlic bulb
gentian root
Gentiana manshurica
Ginsenosides
glucose
Glycochenodeoxycholic acid
Glycocholic acid
Glycyrrhetinic acid
Glycyrrhizin
gooseberry
green tea
Guggulsterones
Gypenoside
herbal blend (proprietary)
hesperetin
isoliquiritigenin
isosilybin
jiaogulan
Jurubeba
kale
Kutkins
L-glutathione
L-methionine
L-ornithine
lecithin
lingzhi
liquid liver fractions
mangiferin
Maslinic acid
Matcha
Milk thistle
Monoterpenes
Mushroom
Myricetin
N-acetyl-cysteine (NAC)
Naringenin
Naringin
Niacin (vitamin B3)
Niacinamide (vitamin B3)
nicotinamide riboside
Nigella seed
Nobiletin
oleanolic acid
olive
ornithine L-aspartic acid
ox bile
Oxymatrine
pantethine
parsley
Pentacyclic triterpenoids
phenolic compounds
Phenylpropanoids
phosphatidylcholine
phospholipids
Phthalides
Phyllanthus
picrorhiza kurroa
Picroside
Plukenetia volubilis
Polydatin
polymethoxylated flavones
polyphenols
pu-er tea
Puerarin
pumpkin
punarnava
riboflavin (vitamin B2)
S-allylcysteine
Salvianolic acid
Schisandrins
Schizandrol A
Scoparia dulcis
Sesamin
Silybin
Silybum
Silychristin
Silydianin
silymarin
Sulforaphane
sulforaphane glucosinolate
Taraxacum
Taurochenodeoxycholic acid
Taurocholic acid
Taurodeoxycholic acid
Taxifolin
Terminalia
Terpenoids
Theabrownin
Thistle
Thymoquinone
tocotrienols
trace minerals
Trimethylglycine (TMG)
Triphala
Triterpenes
turmeric
vitamin B
Watercress
Wogonin
Xanthohumol
Xanthorrhizol
Yin Chen
Zinc

Other body systems supported by dihydrolipoic acid

Blood
Brain
Circulatory System
Heart
Hepatic System
Immune System
Liver
Mitochondria
Nerves
Skin

Products containing dihydrolipoic acid

We currently have no products on Vitabase that contain this ingredient.