Evidence supporting the use of: Glycochenodeoxycholic acid
For the body system: Hepatic System
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Glycochenodeoxycholic acid (GCDCA) is a primary bile acid naturally produced in the liver, conjugated from chenodeoxycholic acid and glycine. Its main biological function is to facilitate the emulsification and absorption of dietary fats and fat-soluble vitamins in the intestine. In clinical contexts, bile acids as a class—including GCDCA—are sometimes used in the management of certain liver and biliary disorders. For example, chenodeoxycholic acid and ursodeoxycholic acid (UDCA) are used therapeutically to dissolve gallstones and treat some cholestatic liver diseases. While GCDCA itself is not commonly administered as a standalone therapeutic agent, it serves as an important biomarker for hepatic function, and its concentrations are measured in the diagnosis and monitoring of liver diseases. Scientific studies have shown that altered bile acid profiles, including increased levels of GCDCA, are associated with hepatic dysfunction such as cholestasis and cirrhosis. However, the primary clinical use of GCDCA is not as a supplement to “support” the liver, but as a diagnostic indicator or as a research tool. There is scientific validation for the central physiological role of GCDCA and other bile acids in hepatic and digestive health, but limited direct evidence for using supplemental GCDCA specifically as a treatment to support liver function in humans.
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Other body systems supported by Glycochenodeoxycholic acid
Digestive SystemGall Bladder
Gastrointestinal Tract
Hepatic System
Intestinal System
Liver