Evidence supporting the use of: Glycocholic acid
For the body system: Hepatic System

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Glycocholic acid is a conjugated bile acid formed from cholic acid and glycine in the liver. Its primary physiological role is to aid in the emulsification and absorption of dietary fats in the small intestine. There is scientific evidence supporting the importance of bile acids, including glycocholic acid, in normal hepatic and digestive function. In clinical medicine, bile acids are sometimes used therapeutically in conditions involving bile acid deficiency or cholestasis, such as in certain liver diseases, although more commonly used bile acids for therapy are ursodeoxycholic acid and chenodeoxycholic acid.

Bile acid supplementation, in general, can support hepatic function by promoting bile flow and preventing bile acid accumulation, which can be toxic to hepatocytes. However, routine supplementation with glycocholic acid specifically is not a standard treatment for liver diseases, and direct clinical trials evaluating glycocholic acid supplementation for hepatic support in humans are limited. Most evidence for bile acids and hepatic support comes from studies on other bile acids, animal models, or indirect evidence from the physiological role of bile acids.

In summary, while the physiological necessity of glycocholic acid in hepatic and digestive function is well established, direct clinical evidence for its use as a supplement to support the hepatic system is moderate but not robust. Thus, the rating reflects the presence of scientific rationale, but a lack of strong direct clinical trial evidence for glycocholic acid supplementation in hepatic support.

More about Glycocholic acid
More about Hepatic System

Other body systems supported by Glycocholic acid

Digestive System
Gall Bladder
Hepatic System
Intestinal System

Products containing Glycocholic acid

We currently have no products on Vitabase that contain this ingredient.