Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Guggulsterone is a plant sterol derived from the resin of the Commiphora mukul tree, commonly known as guggul. Its use to support the hepatic (liver) system is primarily based on traditional Ayurvedic medicine, where guggul has been used for centuries to treat a range of ailments, including those related to liver health such as jaundice and “liver sluggishness.” The rationale in traditional medicine is that guggul helps detoxify the body and stimulate liver function.

Modern scientific evidence supporting its efficacy for liver support is limited and inconclusive. Some preclinical studies in animals have indicated that guggulsterone may have hepatoprotective effects, such as reducing markers of liver damage or oxidative stress. However, these studies are generally preliminary, with few high-quality human clinical trials directly evaluating its impact on liver health or function. Most contemporary research on guggulsterone has focused on its potential cholesterol-lowering effects rather than direct hepatic support.

Overall, while there is a long tradition of guggul use for liver health in Ayurveda, robust scientific validation is lacking. Its use for hepatic support should therefore be seen as primarily traditional, with limited scientific endorsement at this time.

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Other body systems supported by Guggulsterone

Blood
Circulatory System
Digestive System
Gall Bladder
Glandular System
Heart
Hepatic System
Joints

Products containing Guggulsterone

We currently have no products on Vitabase that contain this ingredient.