Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Synopsis

L-glutathione is a tripeptide composed of glutamine, cysteine, and glycine, and is one of the most important endogenous antioxidants in the human body. It plays a critical role in hepatic (liver) health by participating in detoxification processes and protecting hepatocytes from oxidative stress and damage. The liver contains high concentrations of glutathione, which is essential for the conjugation and elimination of toxins, drugs, and metabolic waste products via the glutathione S-transferase pathway.

Numerous scientific studies have demonstrated that glutathione levels are often depleted in cases of liver disease, such as non-alcoholic fatty liver disease (NAFLD), alcoholic liver disease, and viral hepatitis. Supplementation with glutathione or its precursors has been shown in some clinical trials and animal studies to help restore hepatic glutathione levels, reduce oxidative damage, and improve certain biomarkers of liver function. Intravenous glutathione has been used in some clinical settings for conditions like acetaminophen toxicity and chronic liver disease, although oral bioavailability is limited and remains a subject of ongoing research.

While the evidence base for oral supplementation in healthy individuals is not as robust as for specific disease states, there is considerable mechanistic and clinical support for glutathione’s role in liver health, especially under conditions of oxidative stress or toxic exposure. Therefore, the justification for using L-glutathione to support the hepatic system is primarily scientific, with a moderate to strong evidence rating.

More about L-glutathione
More about Hepatic System

Other ingredients that support Hepatic System

Other body systems supported by L-glutathione

Products containing L-glutathione

Thorne Advanced Digestive Enzymes Bio-Gest
Designs For Health Amino-D-Tox™
Designs For Health Amino-D-Tox™
Metagenics BioPure Protein® Powder
Metagenics Bone Builder Active
Integrative Therapeutics Detoxication Factors
Metagenics Echinacea Synergy
Douglas Laboratories Free Form Amino
Integrative Therapeutics Glutathione Cell Defense
Thorne Glutathione-SR NSF
Metagenics ImmuCore
Metagenics Immune Defense Pack
Integrative Therapeutics K-PAX MitoNutrients
Designs For Health L-Glutathione Power™
Pure Encapsulations Liposomal Glutathione
Pure Encapsulations Liposomal Glutathione
Designs For Health Liposomal Glutathione
Douglas Laboratories Liposomal Glutathione
Pure Encapsulations Liposomal Glutathione
Pure Encapsulations Macular Support Formula
Pure Encapsulations Macular Support Formula
Thorne MediClear Plus
Designs For Health Metal-X-Synergy™
Designs For Health NOx Synergy™
Designs For Health PaleoCleanse Plus™
Designs For Health PaleoCleanse Plus™
Designs For Health PaleoCleanse Plus™ Detox Program
Designs For Health PaleoCleanse Plus™Chocolate Detox Kit
Integrative Therapeutics Panplex 2-Phase
Metagenics Perfect Protein® Pea & Rice Chocolate Powder
Metagenics Perfect Protein Pea & Rice Vanilla Powder
Metagenics Perfect Protein Whey Chocolate
Metagenics Perfect Protein Whey Vanilla
Designs For Health Plant Protein Cleanse
Designs For Health Plant Protein Cleanse Plus™ 570g
Vitabase Prostate Complex (Formerly Prostate Complete)
Designs For Health Prostate Supreme™
Designs For Health Prostate Supreme™
Integrative Therapeutics ProThrivers Wellness Flav Complex
Pure Encapsulations Reduced Glutathione
Pure Encapsulations Reduced Glutathione
Designs For Health S-Acetyl Glutathione Synergy
Vitabase Super Antioxidant Formula
Metagenics Ultra Glucose Control® Chocolate
Metagenics Ultra Glucose Control Chocolate
Metagenics Ultra Glucose Control Vanilla
Metagenics Ultra Glucose Control Vanilla
Metagenics Ultra Potent-C 500
Metagenics Ultra Potent-C Powder
Metagenics Ultra Prostagen Concentrated
Pure Encapsulations Ultra Pure Pack
Metagenics UltraGI Replenish® Chocolate
Metagenics UltraGI Replenish Chocolate
Metagenics UltraGI Replenish Vanilla
Metagenics UltraGI Replenish Vanilla
Metagenics UltraInflamX Plus 360°® Chocolate/Orange
Metagenics UltraInflamX Plus 360° Mango
Metagenics UltraInflamX Plus 360° Mango
Metagenics UltraInflamX Plus 360° Orange
Metagenics UltraInflamX Plus 360° Original Spice
Metagenics UltraInflamX Plus 360° Pineapple/Banana
Metagenics UltraInflamX Plus 360° Pineapple/Banana
Metagenics UltraMeal Advanced Protein® Dutch Chocolate
Metagenics UltraMeal Advanced Protein French Vanilla
Metagenics UltraMeal Advanced Protein Plain
Metagenics UltraMeal Cardio 360°® Pea/Rice Chocolate
Metagenics UltraMeal Cardio 360° Pea/Rice Vanilla
Pure Encapsulations UltraNutrient®
Pure Encapsulations UltraNutrient®
Pure Encapsulations UltraNutrient®
Douglas Laboratories Uro-Pro ®
Vitabase Vision Support