Evidence supporting the use of: Lecithin
For the body system: Hepatic System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lecithin (often derived from soy or egg yolk) is a source of phospholipids, including phosphatidylcholine, which are important components of cell membranes. Its use in supporting the hepatic (liver) system has some basis in scientific research, though evidence is limited and not robust. Phosphatidylcholine, a major constituent of lecithin, is involved in the synthesis and export of very-low-density lipoprotein (VLDL) in the liver, which is necessary for the transport of fat from the liver to other tissues. Some studies, including small clinical trials and animal research, suggest that phosphatidylcholine supplementation may help protect against liver damage, fatty liver disease (hepatic steatosis), and support liver repair, particularly in cases of alcohol-induced liver injury or non-alcoholic fatty liver disease (NAFLD). However, results are mixed and most high-quality clinical trials have not demonstrated consistent, significant benefits. The European Food Safety Authority (EFSA) and other regulatory agencies have not approved lecithin or phosphatidylcholine supplements for liver health claims, citing insufficient evidence. In summary, while there is a scientific rationale and some preliminary evidence for lecithin’s support of the hepatic system, the strength of evidence is modest, and further well-designed human trials are needed to establish its efficacy.

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Other body systems supported by lecithin

Acetylcholine
Brain
Gall Bladder
Hepatic System
Liver
Nerves