Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Liquid liver fractions, derived from animal liver (usually bovine), have a long history of use in traditional health practices and early 20th-century nutritional supplementation. Traditionally, they have been used as a general tonic for vitality, energy, and to support liver health, primarily due to the dense concentration of nutrients found in liver tissue, including B vitamins (especially B12), iron, and various amino acids. The rationale for their use in supporting the hepatic system centers on the concept of "like supports like" — consuming liver to strengthen one's own liver function. Historically, liquid liver extracts were even prescribed for anemia and general debility before the widespread availability of synthetic vitamins and minerals.

However, there is minimal modern scientific evidence specifically validating the use of liquid liver fractions to support hepatic function in healthy individuals. Most contemporary research supporting liver health focuses on other compounds (such as silymarin from milk thistle) rather than liver fractions. Some evidence from the mid-20th century does show that liver extracts can correct certain nutritional deficiencies, but these do not directly equate to enhanced liver function. Thus, the primary justification for their use is based on tradition and nutritional content, rather than rigorous scientific validation for hepatic support.

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