Evidence supporting the use of: Monounsaturated fatty acid (unspecified)
For the body system: Hepatic System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Monounsaturated fatty acids (MUFAs), found in foods such as olive oil, avocados, and certain nuts, have scientific evidence supporting their role in supporting the hepatic (liver) system. Research over the past several decades has demonstrated that diets rich in MUFAs can help improve liver health, particularly in the context of non-alcoholic fatty liver disease (NAFLD). Clinical studies have shown that replacing saturated fats with MUFAs can reduce liver fat accumulation, improve insulin sensitivity, and decrease markers of liver inflammation. For example, a 2017 review in World Journal of Gastroenterology discussed how MUFA-rich diets, like the Mediterranean diet, are associated with lower risk of NAFLD and better outcomes in patients with existing liver conditions.

MUFAs are thought to exert these hepatoprotective effects by modulating lipid metabolism, reducing oxidative stress, and improving the lipid profile (such as lowering LDL cholesterol and increasing HDL cholesterol). While more research is needed to define optimal intake and long-term effects, the current body of evidence supports the use of MUFAs as part of a healthy dietary pattern for liver support. Therefore, the use of monounsaturated fatty acids to support the hepatic system is justified by scientific evidence, particularly for individuals at risk of or suffering from metabolic liver diseases.

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