Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Picroside is a major active compound found in the plant Picrorhiza kurroa, which has been used in traditional Ayurvedic medicine for centuries to support liver health and treat various hepatic disorders. In Ayurveda, Picrorhiza kurroa (known as Kutki) is considered a potent "hepatoprotective" herb and is commonly prescribed for conditions like jaundice, hepatitis, and liver dysfunction.

Some modern preclinical studies (mainly in animal models and in vitro experiments) have identified potential hepatoprotective, antioxidant, and anti-inflammatory effects of picrosides, particularly picroside I and II. These studies suggest that picrosides may help protect liver cells from damage induced by toxins and oxidative stress. However, robust clinical trials in humans are limited, and the evidence base remains incomplete. Systematic reviews often conclude that while there is promising preclinical data, high-quality human studies are lacking.

Therefore, the use of picroside for hepatic support is primarily justified by a long history of traditional use, with some suggestive but not conclusive scientific support. Its role in supporting the hepatic system is recognized in herbal medicine, but mainstream medical guidelines do not endorse its use due to insufficient clinical evidence.

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alpha-lipoic acid
amino acids
AMP-activated protein kinase (AMPK)
ampelopsin
andrographolide
animal protein
Antrodia camphorata
apigenin
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artichoke
baicalein
barberry
Basidiomycota
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berberine
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betanin
bile acid
bile salt
bitter principals
black garlic
black seed
Boerhavia diffusa
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bovine
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capillary artemisia
carqueja
catalpol
chanca piedra
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chlorogenic acid
cholic acid
Coenzyme A
corilagin
cruciferous
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curcumin
Curcuminoid
cynarin
cynaropicrin
d-glucarate
dandelion
dehydrocholic acid
dihydrolipoic acid
dihydromyricetin
dithiolthiones
DL-Methionine
Eclipta
egg
emblicanin
epigallocatechin gallate (EGCG)
eriocitrin
ferulic acid
flavonolignan
fringetree
fungus
gallate
gamma-glutamylcysteine
ganoderma
garlic bulb
gentian root
Gentiana manshurica
Ginsenosides
glucose
Glycochenodeoxycholic acid
Glycocholic acid
Glycyrrhetinic acid
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gooseberry
green tea
Guggulsterones
Gypenoside
herbal blend (proprietary)
hesperetin
isoliquiritigenin
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jiaogulan
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L-methionine
L-ornithine
lecithin
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mangiferin
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nicotinamide riboside
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oleanolic acid
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pantethine
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Pentacyclic triterpenoids
phenolic compounds
Phenylpropanoids
phosphatidylcholine
phospholipids
Phthalides
Phyllanthus
picrorhiza kurroa
Picroside
Plukenetia volubilis
Polydatin
polymethoxylated flavones
polyphenols
pu-er tea
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pumpkin
punarnava
riboflavin (vitamin B2)
S-allylcysteine
Salvianolic acid
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silymarin
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tocotrienols
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Trimethylglycine (TMG)
Triphala
Triterpenes
turmeric
vitamin B
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Zinc

Other body systems supported by Picroside

Digestive System
Gall Bladder
Gastrointestinal Tract
Hepatic System
Immune System
Kidneys
Liver
Spleen

Products containing Picroside

We currently have no products on Vitabase that contain this ingredient.