Evidence supporting the use of: Taurochenodeoxycholic acid
For the body system: Hepatic System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Taurochenodeoxycholic acid (TCDCA) is a taurine-conjugated form of chenodeoxycholic acid, one of the primary bile acids synthesized in the liver. Its role in supporting the hepatic system is scientifically validated, as bile acids are crucial for several liver functions, including the emulsification and absorption of dietary fats, regulation of cholesterol homeostasis, and modulation of metabolic and inflammatory pathways within the liver. TCDCA, like other bile acids, facilitates the excretion of cholesterol and bilirubin, and supports the digestion and absorption of fat-soluble vitamins. Additionally, bile acids, including TCDCA, act as signaling molecules regulating liver metabolism and have been shown to activate specific nuclear receptors such as FXR (farnesoid X receptor), which plays a role in maintaining hepatic and systemic metabolic balance.

Scientific studies have demonstrated that supplementation or therapeutic use of bile acids (especially ursodeoxycholic acid and chenodeoxycholic acid, and their conjugates) can support liver health in certain cholestatic disorders and may help restore bile flow or reduce toxic bile acid accumulation. While TCDCA is less commonly used directly in clinical practice compared to its unconjugated form, its biochemical role in hepatic physiology is well characterized. However, most clinical interventions utilize other bile acids, and TCDCA is primarily studied in experimental or animal models. Despite this, the evidence supporting the role of TCDCA and related bile acids in liver function is robust, justifying a high evidence rating.

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Other body systems supported by Taurochenodeoxycholic acid

Digestive System
Gall Bladder
Gastrointestinal Tract
Hepatic System
Intestinal System
Liver

Products containing Taurochenodeoxycholic acid

We currently have no products on Vitabase that contain this ingredient.