Evidence supporting the use of: Triterpenoid (unspecified)
For the body system: Hepatic System

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Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Triterpenoids are a large class of naturally occurring compounds found in many medicinal plants, such as licorice (Glycyrrhiza glabra), Ganoderma lucidum (Reishi mushroom), and Centella asiatica. Traditionally, these compounds have been used in herbal medicine systems, especially in Asia, for their perceived hepatoprotective (liver-protecting) properties. Historical texts from Traditional Chinese Medicine and Ayurveda reference the use of triterpenoid-rich plants for supporting liver health, treating hepatitis, and protecting against toxins.

While there is some modern research suggesting certain triterpenoids (such as glycyrrhizin from licorice or ganoderic acids from Reishi) may have hepatoprotective and anti-inflammatory effects in cell and animal models, the body of clinical evidence in humans remains limited and is often not specific to "triterpenoids" as a general group, but rather to individual compounds or extracts. Therefore, the primary justification for using unspecified triterpenoids to support the hepatic system is based on traditional use, with moderate support from preclinical studies. More rigorous human clinical trials are needed to validate their efficacy and safety for liver health.

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