Evidence supporting the use of: Vitamin B5 (pantethine)
For the body system: Hepatic System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Pantethine, a derivative of vitamin B5 (pantothenic acid), has been studied for its effects on lipid metabolism and liver function, which are key aspects of hepatic (liver) health. Pantethine serves as a precursor to coenzyme A, a molecule critical for fatty acid metabolism in the liver. Several clinical studies have shown that pantethine supplementation can help reduce total cholesterol, LDL cholesterol, and triglyceride levels, which can indirectly benefit liver health by reducing fat accumulation and the risk of non-alcoholic fatty liver disease (NAFLD).

While these lipid-lowering effects are relatively well-documented, direct evidence of pantethine’s benefits in treating or preventing liver diseases is limited. Some animal studies suggest that pantethine may help protect against certain types of liver injury and oxidative stress, but robust, large-scale human trials specifically examining liver outcomes are lacking. Most of the available evidence is focused on its cardiovascular benefits, with hepatic support being a secondary consideration.

In summary, the use of pantethine to support the hepatic system has a scientific basis, primarily due to its role in lipid metabolism and some preliminary evidence of liver protection in animal models. However, more targeted research is needed to fully validate its efficacy for specific liver conditions in humans.

More about Vitamin B5 (pantethine)
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Other body systems supported by Vitamin B5 (pantethine)

Adrenal Cortex
Adrenal Glands
Circulatory System
Heart
Hepatic System
Liver

Products containing Vitamin B5 (pantethine)

We currently have no products on Vitabase that contain this ingredient.