Evidence supporting the use of: Vitamin E (delta-tocotrienol)
For the body system: Hepatic System

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Delta-tocotrienol, a member of the vitamin E family, has garnered increasing scientific interest for its potential hepatoprotective effects. Preclinical studies, primarily in animal models, have demonstrated that delta-tocotrienol can reduce hepatic inflammation, lipid accumulation, and oxidative stress—key features of liver diseases such as non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). The mechanisms are thought to involve the modulation of lipid metabolism, suppression of pro-inflammatory cytokines, and enhancement of antioxidant defenses within liver cells.

Some early phase human clinical studies have also suggested that tocotrienol supplementation may improve liver function markers (such as ALT and AST) and reduce hepatic fat content in individuals with NAFLD. However, these studies are generally small in scale and further large-scale, well-controlled clinical trials are needed to confirm these findings. At present, delta-tocotrienol is not a standard treatment for liver diseases, but the accumulating scientific evidence suggests a promising adjunctive role, especially in metabolic liver disorders.

In summary, while there is no long-standing traditional use of delta-tocotrienol for liver health, scientific validation—primarily from animal and preliminary human studies—supports its potential benefit for the hepatic system. The evidence is promising but not yet definitive, meriting a moderate rating.

More about Vitamin E (delta-tocotrienol)
More about Hepatic System

Products containing Vitamin E (delta-tocotrienol)

We currently have no products on Vitabase that contain this ingredient.