Evidence supporting the use of: Andrographolide
For the health condition: Hepatitis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Andrographolide, a bioactive compound isolated from the plant Andrographis paniculata, has been studied for its potential hepatoprotective effects, including its use in supporting or treating hepatitis. Several preclinical studies (in vitro and in vivo) have demonstrated that andrographolide exhibits anti-inflammatory, antioxidant, and antiviral properties. These effects are believed to be beneficial in mitigating liver injury and inflammation associated with hepatitis.

Specifically, andrographolide has been shown in animal models to reduce markers of liver damage (such as ALT and AST), decrease liver fibrosis, and modulate immune responses. Some studies have also suggested antiviral activity against hepatitis B virus (HBV), with mechanisms involving inhibition of viral replication and modulation of immune response. However, the bulk of the evidence comes from laboratory and animal studies rather than large, well-controlled human clinical trials.

Limited clinical studies in humans have suggested that Andrographis paniculata preparations may help improve liver function parameters in patients with hepatitis, but these studies are generally small and of variable quality. While the scientific rationale for andrographolide’s use in hepatitis is supported by preclinical data, the clinical evidence in humans remains insufficient for strong recommendations. Thus, while there is scientific basis for interest and ongoing research, the current level of evidence supporting its use in hepatitis is moderate but not definitive.

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Other ingredients used for Hepatitis

Achyranthes
Aerva lanata
Agrimonia pilosa
AHCC
Ajuga
Albumin
Algae
American Liverleaf
Andrographis
andrographolide
Angelica
Antrodia camphorata
aster root
astragalin
astragaloside
astragalus
atractylone
aucubin
Auricularia
Baccharoides anthelmintica
bacteria
bael
baicalin
Basidiomycota
Bassia scoparia
bayleaf
BCAA
Bergenia
bergenin
betulinic acid
bitter grass
black cumin
black root
black seed
blackboard tree
Bombax
Borassus aethiopum
borassus palm
borotutu
branched-chain amino acids
Broussonetia
Bupleurum
bupleurum falcatum
burdock
C-phycocyanin
Caesalpinia crista
Carthamus
cat's claw
caterpillar mushroom
Celosia
chaga mushroom
Chinese fleeceflower
Chinese silkvine
chirata
Clerodendrum indicum
commiphora
Coptis chinensis
cordyceps
corilagin
coriolus mushroom
Cynodon dactylon
cytokines
dandelion
Desmodium
Dianthus
Ficus simplicissima
flat-stem milk-vetch
flavonolignan
Flueggea suffruticosa
fucoidan
ganoderma
Globulins
Glucan peptides
Glutathione
Glycyrrhetinic acid
Glycyrrhizin
green chiretta
Hygrophila
Hyperoside
Immunoglobulin G
Indian bael
Indian coraltree
isosilybin
jujube
knotweed
L-cysteine
L-glutathione
labrador tea
Lactoferrin
Lentinula edodes mycelia
lichen
licorice root
Ligustrum
lingzhi
liquid liver fractions
little ironweed
Marine lipid
Milk thistle
Momordica
Morning glory
Morus
Myrrh
N-acetyl-cysteine (NAC)
Neoandrographolides
Nymphaea nouchali
oleanolic acid
omega-3 fatty acids
Onosma bracteatum
oregon grape
ornithine L-aspartic acid
Oroxylum indicum
Oxymatrine
pagoda tree
Palo Azul
parsley
Patrinia
paw paw
peony
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Picroside
Pluchea
plum fruit
Polygonum
polysaccharides
Portulaca
prebiotic blend (proprietary)
protein
punarnava
reishi mushroom
rhubarb
rice
Rubia cordifolia
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sarsaparilla
Schisandrins
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seaweed
selenium
shiitake mushroom
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silymarin
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Products containing andrographolide

We currently have no products on Vitabase that contain this ingredient.