Balsam pear (Momordica charantia), also known as bitter melon, has a long history of use in traditional medicine systems, particularly in Asia, Africa, and the Caribbean. Its use for liver ailments, including hepatitis, is rooted primarily in traditional herbal medicine practices. In traditional Chinese medicine and Ayurveda, Balsam pear is believed to possess "cooling" properties and is used to 'cleanse' the liver and support liver function. Folk practitioners have recommended its juice or extracts for jaundice and other liver disorders, including hepatitis, for centuries.

However, scientific validation for these uses is limited. Preclinical studies have demonstrated that Balsam pear may have hepatoprotective effects in animal models, potentially due to its antioxidant and anti-inflammatory properties. These studies suggest possible mechanisms through which Balsam pear might benefit liver health, such as reducing oxidative stress and modulating immune responses. Nevertheless, clinical trials in humans specifically evaluating its efficacy and safety in treating hepatitis are lacking, and no regulatory body endorses its use for this condition.

In summary, while Balsam pear’s use in hepatitis is justified by tradition and supported by some preliminary laboratory research, robust clinical evidence is absent. Its role in hepatitis management remains a traditional practice rather than a scientifically validated therapy.