Cynodon dactylon (commonly known as Bermuda grass or durva grass) has been used in various traditional systems of medicine, including Ayurveda and Siddha, for the treatment of liver disorders such as hepatitis. The traditional rationale is based on its believed hepatoprotective, anti-inflammatory, and detoxifying properties. Preparations from the whole plant, especially the juice of the grass, are administered orally for liver ailments and jaundice, which is often associated with hepatitis.

Scientific evidence supporting the efficacy of Cynodon dactylon for hepatitis is limited. Some animal studies have shown that extracts of the plant possess hepatoprotective effects against chemically induced liver damage, with observed improvements in liver enzyme profiles and liver histology. These effects are often attributed to antioxidant compounds and flavonoids present in the plant. However, there are no robust clinical trials or extensive human studies that directly demonstrate its safety and efficacy in treating hepatitis (particularly viral hepatitis) in humans.

In summary, the use of Cynodon dactylon for hepatitis is primarily justified by tradition, with only preliminary scientific evidence from animal models and in vitro studies. The absence of high-quality human clinical data means that its use for hepatitis cannot be considered evidence-based at present.