Evidence supporting the use of: Honduran Sarsaparilla
For the health condition: Hepatitis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Honduran Sarsaparilla (Smilax regelii, sometimes referenced as Smilax officinalis) has a long history of use in traditional medicine systems across Central and South America. One of its many folk uses includes support for liver health and treatment of hepatitis. The traditional rationale is based on sarsaparilla's perceived "blood-purifying" properties and its use as a general tonic for various ailments, including liver disorders. However, there is minimal direct scientific evidence substantiating its efficacy specifically for hepatitis. The primary compounds in sarsaparilla, such as saponins and flavonoids, have demonstrated anti-inflammatory and antioxidant properties in general laboratory studies, but clinical trials on hepatitis (especially in humans) are lacking.

Most references to sarsaparilla in the context of hepatitis are found in ethnobotanical surveys or traditional herbal formularies, not in peer-reviewed medical research. Therefore, the use of Honduran Sarsaparilla for hepatitis is best characterized as traditional, with a low evidence rating due to the absence of rigorous clinical validation. Users should exercise caution and consult healthcare providers, as reliance on traditional remedies without adequate scientific backing can be risky, especially for serious conditions like hepatitis.

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