Evidence supporting the use of: Sophora
For the health condition: Hepatitis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

The use of Sophora species (such as Sophora flavescens, known as Kushen in traditional Chinese medicine) for hepatitis is primarily justified by tradition rather than strong scientific evidence. In Chinese, Japanese, and Korean herbal medicine systems, extracts from the root of Sophora flavescens have been used for centuries to "clear heat" and "remove toxins," terms that are often interpreted as actions against infectious and inflammatory diseases, including hepatitis. Historical texts and classical herbal compendia describe Sophora preparations as aids in reducing jaundice, alleviating liver discomfort, and supporting liver function. The traditional rationale is based on empirical use and the herb’s perceived effects rather than modern biomedical understanding.

While there are some preclinical studies indicating that certain alkaloids and flavonoids in Sophora species may have antiviral and hepatoprotective effects in vitro or in animal models, robust clinical evidence in humans remains limited. Most clinical reports are anecdotal or based on small, uncontrolled studies. Therefore, although Sophora is traditionally used to support or treat hepatitis, the overall quality of evidence is low, and its use should be considered as adjunctive rather than primary therapy. Further rigorous clinical trials are needed to confirm efficacy and safety for hepatitis treatment.

More about Sophora
More about Hepatitis

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black cumin
branched-chain amino acids
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bupleurum falcatum
burdock
cat's claw
caterpillar mushroom
chaga mushroom
Coptis chinensis
cordyceps
turmeric
dandelion
knotweed
jujube
L-cysteine
L-glutathione
lactoferrin
lentinula edodes mycelia
licorice root
liquid liver fractions
marine lipid
milk thistle
n-acetyl-cysteine (NAC)
oleanolic acid
omega-3 fatty acids
oregon grape
parsley
plum fruit
prebiotic blend (proprietary)
protein
reishi mushroom
selenium
shiitake mushroom
silymarin
spirulina
turkey tail mushroom
vitamin C
vitamin E
seaweed
zinc
sarsaparilla
Indian bael
punarnava
commiphora
tinospora cordifolia
blackboard tree
caesalpinia crista
rubia cordifolia
swertia
peony
lingzhi
Szechuan lovage
morus
myrrh
ganoderma
aster root
paw paw
Algae
Angelica
Antrodia camphorata
Achyranthes
Auricularia
AHCC
Ajuga
Aucubin
Andrographolide
Albumin
Aerva lanata
American Liverleaf
Astragaloside
Andrographis
Agrimonia pilosa
Astragalin
Atractylone
Black Seed
Borotutu
Broussonetia
bergenin
Betulinic acid
Bayleaf
Bitter Grass
Bael
Basidiomycota
Baccharoides anthelmintica
Bombax
Borassus Palm
Borassus aethiopum
Bacteria
Black root
BCAA
Bupleurum
Baicalin
Bassia scoparia
Bergenia
Chinese Silkvine
Coriolus mushroom
Chinese Fleeceflower
C-Phycocyanin
Chirata
Corilagin
Cytokines
Cynodon dactylon
Carthamus
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Flueggea suffruticosa
Flat-stem milk-vetch
Ficus simplicissima
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Glucan peptides
Globulins
Glutathione
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Glycyrrhizin
Hyperoside
Hygrophila
Immunoglobulin G
Isosilybin
Indian Coraltree
Lichen
Ligustrum
Labrador Tea
Little ironweed
Momordica
Morning Glory
Neoandrographolides
Nymphaea nouchali
Oroxylum indicum
Onosma bracteatum
Oxymatrine
Ornithine l-aspartic acid
Phellodendron
Picroside
Polysaccharides
Pagoda Tree
Pluchea
portulaca
Patrinia
Polygonum
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Sophora
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Products containing Sophora

We currently have no products on Vitabase that contain this ingredient.