Evidence supporting the use of: Ellagic acid
For the health condition: Herpes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Ellagic acid is a polyphenolic compound found in various fruits and nuts, such as pomegranates, strawberries, and walnuts. Its use in supporting or treating herpes (specifically herpes simplex virus, HSV) is justified to a limited extent by preliminary scientific evidence. Laboratory (in vitro) studies have demonstrated that ellagic acid possesses antiviral properties, including activity against HSV-1 and HSV-2. For example, some studies have shown that ellagic acid can inhibit the replication of HSV in cultured cells, possibly by interfering with viral entry or replication processes. These findings have prompted interest in ellagic acid as a potential natural antiviral agent.

However, the evidence is mostly confined to preclinical studies—cell cultures and, to a lesser extent, animal models. There is currently a lack of high-quality clinical trials in humans to confirm efficacy or safety for the treatment or prevention of herpes infections. As such, while the scientific rationale exists based on mechanistic and laboratory research, the evidence remains preliminary. No major health organizations endorse ellagic acid as a treatment for herpes, and it should not replace standard antiviral medications. In summary, ellagic acid's use for herpes is supported by some scientific investigations, but the overall strength of evidence is low (rated 2 out of 5), and further research is needed to establish clinical relevance.

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Products containing ellagic acid

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