Evidence supporting the use of: Reishi mushroom
For the health condition: Herpes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Reishi mushroom (Ganoderma lucidum) has been traditionally used in East Asian medicine for its immune-modulating and antiviral properties. More recently, scientific studies have begun to explore its effects against various viral infections, including herpes simplex virus (HSV). In vitro (test tube) studies have demonstrated that certain extracts from reishi mushroom can inhibit the replication of HSV-1 and HSV-2, the viruses responsible for oral and genital herpes, respectively. The proposed mechanisms include direct virucidal activity, inhibition of viral adsorption or penetration into host cells, and immune system enhancement through the stimulation of natural killer cells and increased production of interferons.

However, most of the evidence for reishi’s efficacy against herpes comes from laboratory studies and animal models. There are very limited clinical trials in humans specifically examining the use of reishi for herpes infections. The lack of robust human data means reishi cannot be recommended as a primary or sole treatment for herpes, but it may be considered as a complementary approach, especially for immune support. Overall, while there is some scientific rationale and preliminary evidence supporting the use of reishi mushroom against herpes, the clinical evidence is not strong, and more research—particularly well-designed human trials—is needed to confirm its effectiveness.

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