Evidence supporting the use of: Anemarrhena
For the health condition: Hot Flashes

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Anemarrhena asphodeloides (known as Zhimu in traditional Chinese medicine) has a long-standing historical use in East Asian herbal medicine, particularly for managing symptoms associated with "Yin deficiency"—a traditional diagnostic category that often includes hot flashes and night sweats, especially in menopausal women. In classical Chinese medicine texts, Anemarrhena is described as having properties that "clear heat and nourish Yin," and it is a common component in formulas like Zhi Bai Di Huang Wan, which is prescribed for menopausal complaints, including hot flashes.

However, scientific evidence directly supporting the use of Anemarrhena for hot flashes is limited. Some laboratory studies and animal models suggest that extracts from Anemarrhena may have estrogenic or anti-inflammatory effects, but robust human clinical trials are lacking. The available scientific literature does not provide high-quality, direct evidence for its efficacy in treating hot flashes. Instead, its use for this condition is primarily based on traditional practice and historical precedent rather than modern clinical validation.

In summary, Anemarrhena is traditionally used to support the management of hot flashes within the framework of Chinese medicine, but rigorous scientific evidence for this use is limited, justifying a moderate evidence rating based on tradition rather than clinical trials.

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