Evidence supporting the use of: Licorice root
For the health condition: Hot Flashes
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Licorice root (Glycyrrhiza glabra) has a long history of use in traditional medicine, including Traditional Chinese Medicine and Ayurveda, for a variety of women's health concerns. Its use for hot flashes is primarily based on tradition rather than robust scientific validation. Historically, it has been included in herbal formulas to "cool" the body and support hormonal balance, especially in menopausal women experiencing vasomotor symptoms like hot flashes and night sweats.
The rationale for its traditional use is linked to its phytoestrogenic properties—compounds in licorice root can weakly bind to estrogen receptors and may help modulate hormonal fluctuations that contribute to hot flashes. Some small clinical studies and animal models suggest potential benefits, but results are inconsistent and the quality of evidence is low. For example, a few small randomized controlled trials have reported reductions in frequency and severity of hot flashes in menopausal women using licorice root extract compared to placebo, but these studies are limited by small sample sizes and methodological concerns.
Overall, licorice root is used traditionally for hot flashes and there is some preliminary scientific interest, but the evidence is not strong or conclusive. Safety is also a concern, as prolonged use can cause side effects such as hypertension and low potassium. Larger, well-designed clinical trials are needed to confirm any efficacy for hot flashes.
Other ingredients used for Hot Flashes
ashwagandhablack cohosh
DHEA (dehydroepiandrosterone)
evening primrose oil
flaxseed
genistein
genistin
licorice root
maca
reishi mushroom
scrophularia root
soybean
vitamin B6
vitamin C
vitamin E
wild yam
red clover
Equol (proprietary)
menthol oil
St. John's Wort
soy isoflavones
27-deoxyactein
8-Prenylnaringenin
Aconite
Anemarrhena
Broussonetia
Bombax
Cohosh
Dong Quai
Estrogen
Isoflavones
Other health conditions supported by licorice root
Abdominal PainAbrasions
Abscesses
Acid Indigestion
Acne
Addictions (general remedies for)
Addictions (tobacco smoking or chewing)
Addison's Disease
Adenitis
Adrenal Fatigue
Afterbirth Pain
Age Spots
Allergies (respiratory)
Amenorrhea
Anal Fistula or Fissure
Anemia
Appetite (deficient)
Asthma
Autoimmune Disorders
Bronchitis
Canker Sores
Chemotherapy (reducing side effects)
Chicken Pox
Cholera
Chronic Obstructive Pulmonary Disorder
Cirrhosis of the Liver
Cold Sores
Colds (antiviral)
Colds (decongestant)
Colds (general)
Colds (prevention)
Colds (with fever)
Colic (adults)
Colic (children)
Colitis
Colon (atonic)
Colon (spastic)
Congestion
Congestion (bronchial)
Congestion (lungs)
Congestion (lymphatic)
Congestion (sinus)
Constipation (adults)
Contagious Diseases
Convalescence
Cough (damp)
Cough (dry)
Cough (general)
Cough (spastic)
Cramps (menstrual)
Crohn's Disease
Croup
Cushing's Disease
Cytomealovirus
Dyspepsia
Eczema
Emphysema
Endometriosis
Enteritis
Epstein Barr Virus
Estrogen (low)
Fatty Liver Disease
Fever
Fibrosis
Gall Bladder (sluggish or removed)
Gall Stones
Gas and Bloating
Gastritis
Gingivitis
Glands (swollen lymph)
Goiter
Gonorrhea
Gout
Grave's Disease
Hair (loss or thinning)
Hair Care (general)
Halitosis
Hangover
Headache (general)
Headache (sinus)
Headache (tension)
Heart (weakness)
Hemorrhoids
Hepatitis
Hernias
Herpes
Hiatal Hernia
Hiccups
Hot Flashes
Hypotension
Hypothyroid
Impetigo
Indigestion
Infection
Infection (bacterial)
Infection (viral)
Inflammation
Inflammatory Bowel Disorders
Influenza
Injuries
Itching
Itching Ears
Jaundice (adults)
Jock Itch
Kidney Infection
Laryngitis
Leaky Gut Syndrome
Leprosy
Lesions
Leucorrhea
Liver Detoxification
Lungs (fluid in)
Lyme Disease
Lymph Nodes or Glands (swollen)
Malaria
Mastitis
Measles
Menopause
Menorrhagia
Menstrual Irregularity
Menstruation (scant)
Mental Illness
Metabolic Syndrome
Mononucleosis
Mood Swings
Morning Sickness
Mumps
Nausea and Vomiting
Nephritis
Nervous Exhaustion
Nervousness
Night Sweating
Nocturnal Emission
Oral Surgery
Ovarian Pain
Overacidity
Pertussis
Pleurisy
PMS (general)
Pneumonia
Poison Ivy or Oak
Rashes and Hives
Rosacea
Sore Throat
Ulcers
Products containing licorice root
Vitabase
7 Day Colon Cleanse
Pure Encapsulations
ADR Formula®
Pure Encapsulations
ADR Formula®
Designs For Health
Adrenotone™
Designs For Health
Adrenotone™
Vitabase
Blood Sugar Formula
Metagenics
CandiBactin BR
Metagenics
CandiBactin-BR
Pure Encapsulations
DGL Plus®
Pure Encapsulations
DGL Plus®
Designs For Health
DGL Synergy™
Metagenics
Echinacea Synergy
Integrative Therapeutics
EHB
Pure Encapsulations
EpiIntegrity
Metagenics
Essential Defense®
Pure Encapsulations
G.I. Fortify
Designs For Health
GastroMend-HP™
Designs For Health
GastroMend-HP™
Thorne
GI Relief GI-Encap
Designs For Health
GI Revive®
Designs For Health
GI Revive®
Metagenics
Glutagenics® powder
Integrative Therapeutics
Heartburn Advantage
Pure Encapsulations
Heartburn Essentials
Pure Encapsulations
Heartburn Essentials
Metagenics
Licorice Plus®
Vitabase
Life's Essentials Plus
Douglas Laboratories
Pylori-Plex
Integrative Therapeutics
Rhizinate
Integrative Therapeutics
Rhizinate-FF
Integrative Therapeutics
Similase Sensitive Stomach
Integrative Therapeutics
Similase Sensitive Stomach
Thorne
Stress Balance Phytisone
Integrative Therapeutics
Super Milk Thistle X
Vitabase
Women's Support