Evidence supporting the use of: Black seed
For the health condition: Hypertension

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Black seed (Nigella sativa) has a long history of use in traditional medicine, including in Middle Eastern and South Asian cultures, for a variety of ailments, hypertension among them. In recent years, there has been increasing scientific interest in its potential antihypertensive effects. Several human clinical trials and animal studies provide moderate evidence supporting black seed’s use in managing high blood pressure. For example, a randomized, double-blind, placebo-controlled study published in the journal Phytotherapy Research (2013) found that daily supplementation with black seed oil for eight weeks led to significant reductions in both systolic and diastolic blood pressure in mildly hypertensive individuals compared to placebo. The proposed mechanisms include black seed’s thymoquinone content, which may exert vasodilatory effects, reduce oxidative stress, and modulate the renin-angiotensin system. Meta-analyses of clinical trials, such as one published in Complementary Therapies in Medicine (2019), have concluded that black seed supplementation is associated with modest but statistically significant reductions in blood pressure, particularly in people with elevated baseline blood pressure. However, the studies to date are relatively small, of short duration, and sometimes vary in the preparation and dosage of black seed used. Thus, while scientific evidence exists, it is not yet robust enough to recommend black seed as a first-line therapy, but it may serve as a complementary approach pending further research.

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Products containing black seed

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