Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Coenzyme Q10 (CoQ10) is supported by scientific evidence for its use in managing hypertension, though the overall strength of evidence is moderate rather than strong. CoQ10 is a naturally occurring antioxidant that plays a crucial role in mitochondrial energy production. Several clinical trials and meta-analyses have investigated its potential antihypertensive effects. A 2007 meta-analysis published in the Journal of Human Hypertension reviewed 12 clinical trials and found that CoQ10 supplementation was associated with a significant reduction in systolic (by about 17 mmHg) and diastolic (by about 10 mmHg) blood pressure in patients with primary hypertension. The proposed mechanism is that CoQ10 improves endothelial function and promotes vasodilation by enhancing nitric oxide availability and reducing oxidative stress.

However, not all studies have shown consistent results, and some more recent research has found smaller or nonsignificant effects. Additionally, the quality of the trials has varied, with some studies having small sample sizes or potential bias. Nonetheless, authoritative sources such as the Mayo Clinic and the American Heart Association acknowledge that CoQ10 appears to have a modest blood pressure-lowering effect and is generally considered safe. CoQ10 is not a first-line treatment for hypertension but may be considered as an adjunct to standard therapy, particularly in patients with mild hypertension or those seeking complementary options. Overall, scientific evidence supports its use, but it should not replace established antihypertensive medications.

More about coenzyme Q10 (CoQ10)
More about Hypertension

Other ingredients used for Hypertension

Other health conditions supported by coenzyme Q10 (CoQ10)

Products containing coenzyme Q10 (CoQ10)

Pure Encapsulations Athletic Nutrients
Douglas Laboratories Citrus-Q10 ™
Douglas Laboratories Co-Enzyme Q10 Softgel
Douglas Laboratories Coenzyme Q-10 with Lipoic Acid
Douglas Laboratories Coenzyme Q-10 with Lipoic Acid
Integrative Therapeutics CoQ10
Integrative Therapeutics COQ10 100 mg Tropical
Pure Encapsulations CoQ10 120 mg
Pure Encapsulations CoQ10 120 mg
Pure Encapsulations CoQ10 120 mg
Integrative Therapeutics COQ10 200 mg Chocolate 30 chew tabs
Pure Encapsulations CoQ10 250 mg
Pure Encapsulations CoQ10 30 mg
Pure Encapsulations CoQ10 500 mg
Pure Encapsulations CoQ10 60 mg
Pure Encapsulations CoQ10 60 mg
Pure Encapsulations CoQ10 60 mg
Pure Encapsulations CoQ10 l-Carnitine Fumarate
Thorne CoQ10 Q-Best 100
Metagenics CoQ10 ST®-100 mg
Metagenics CoQ10 ST-100 mg
Metagenics CoQ10 ST-200 mg
Integrative Therapeutics Detoxication Factors
Integrative Therapeutics Detoxication Factors
Pure Encapsulations Energize Plus™ Pure Pack
Pure Encapsulations Hair/Skin/Nails Ultra
Thorne Heart Health Complex Q-10 Plus
Integrative Therapeutics K-PAX MitoNutrients
Vitabase Life's Essentials Plus
Designs For Health Mito-NR™
Pure Encapsulations Mitochondria-ATP
Designs For Health Mitochondrial NRG™
Pure Encapsulations NeuroMood Pure Pack
Metagenics NutraGems® CoQ10 300
Pure Encapsulations O.N.E.™ Multivitamin
Pure Encapsulations O.N.E.™ Multivitamin
Pure Encapsulations O.N.E.™ Multivitamin
Thorne Omega-3 w/ CoQ10
Thorne Ovarian Care
Integrative Therapeutics ProThrivers Wellness Flav Complex
Pure Encapsulations PureGenomics® UltraMultivitamin
Designs For Health Q-Evail® 100
Designs For Health Q-Evail® 200
Pure Encapsulations Q-Gel® (Hydrosoluble™ CoQ10) 100 mg
Thorne Red Yeast Rice + CoQ10 Choleast
Pure Encapsulations Renual
Pure Encapsulations RevitalAge™ Nerve
Pure Encapsulations RevitalAge™ Ultra
Designs For Health RYR Synergy™
Pure Encapsulations SR-CoQ10 with PQQ
Vitabase Super Fat Burner
Pure Encapsulations Ubiquinol-QH 100 mg
Pure Encapsulations Ubiquinol-QH 200 mg
Pure Encapsulations Ubiquinol VESIsorb®
Integrative Therapeutics UBQH 100 mg
Douglas Laboratories Ultra Preventive 50+ -EZ Swallow
Douglas Laboratories Ultra Preventive One Daily
Pure Encapsulations Ultra Pure Pack
Pure Encapsulations UltraDetox 10-Day Pure Pack
Pure Encapsulations UltraNutrient®
Pure Encapsulations UltraNutrient®
Pure Encapsulations UltraNutrient®
Metagenics Wellness Essentials Brain Health Daily Packs