Evidence supporting the use of: Grape
For the health condition: Hypertension
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Grapes, particularly red and purple varieties, are scientifically investigated for their potential benefits in managing hypertension (high blood pressure). The primary compounds of interest are polyphenols, especially flavonoids and resveratrol, which are abundant in grape skins and seeds. Several clinical studies suggest that these compounds may improve endothelial function, reduce oxidative stress, and promote vasodilation by increasing nitric oxide availability, all of which can contribute to lower blood pressure.
A number of randomized controlled trials have evaluated grape or grape-derived products, such as grape seed extract and grape juice, for their impact on blood pressure. For example, a meta-analysis published in the journal PLoS One (2016) found a modest but statistically significant reduction in systolic and diastolic blood pressure among adults consuming grape polyphenols. However, the effects are generally mild and may be more pronounced in individuals with prehypertension or mild hypertension.
Traditionally, grapes have been consumed as part of a healthy diet, but their specific use for hypertension is primarily supported by modern scientific research rather than historical herbal medicine practices. The overall evidence base rates as moderate (3/5), with more research needed to confirm optimal dosages and long-term effects. Grapes and their extracts are best considered as part of a broader lifestyle approach to cardiovascular health.
Other ingredients used for Hypertension
acai berryalfalfa
algal oil
alpha-linolenic acid (ALA)
anthocyanins
arjun tree
ashwagandha
asparagus
astaxanthin
astragalus
banaba
barley
beet
berberine
bergamot
berry flavor
beta caryophyllene
Beta-Glucan
bilberry
black cumin
black currant
black garlic
radish
sesame
black tea
blackberry
blueberry
bonito peptide
broccoli
rice
brussel sprouts
bupleurum falcatum
calcium
canola oil
cat's claw
catechins
caterpillar mushroom
catjang cowpea
cauliflower
celery
cherry
chia seed
Chinese salvia root
chlorella
chokeberry
cinnamon
citrus bioflavonoids
citrus sinensis (proprietary)
coenzyme Q10 (CoQ10)
coleus forskohlii
collard
cucumber
daidzin
diallyl disulfide (DADS)
diallyl trisulfide (DATS)
melon
eleuthero
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish oil
fish protein
flaxseed
forskohlii root
fruit and vegetable blend (proprietary)
gooseberry
gotu kola
grape
green tea
greens blend (proprietary)
hawthorn
hesperetin
hesperidin
hibiscus
jujube
kale
kudzu
l-arginine
l-citrulline
l-taurine
lactium casein decapeptide
lactobacillus gasseri
lactobacillus helveticus
lentinula edodes mycelia
linoleic acid (LA)
luteolin
lycopene
mackerel
magnesium
maitake mushroom
mango
marine lipid
matcha
melatonin
moringa
motherwort
naringin
nattokinase
nettle
oat
okra
oleanolic acid
oleic acid
olive
omega-3 fatty acids
omega-9 fatty acids
ophiopogon root
orange
oyster mushroom
pantethine
perilla
pine bark
plum fruit
pomegranate
pomelo
potassium
prebiotic blend (proprietary)
psyllium
quail egg
quercetin
quinoa
red yeast rice
redcurrant
rehmannia glutinosa
reishi mushroom
resveratrol
rutin
rye
safflower oil
saffron
sardines
shiitake mushroom
black ginger
soybean
spinach
spirulina
stevia
strawberry
tocotrienols
tomato
almond fruit
ubiquinol
vegetable and fruit blend (proprietary)
vegetable blend (proprietary)
vitamin C
vitamin D
vitamin D3
seaweed
watermelon
mulberry
jiaogulan
capsicum
inula racemosa
tinospora cordifolia
blackboard tree
lingzhi
morus
sunflower
ferulic acid
chrysanthemum
cistanche
dioscorea
eucommia
ganoderma
lotus seed
purslane
coix
noni
goji berry
amaranth
millet seed
algae
kidney beans
cocoa
chickpea protein
AMP-activated protein kinase (AMPK)
soy isoflavones
ashitaba
soursop
Arugula
Arjuna
Apigenin
Aronia melanocarpa
Allicin
Auricularia
Autumn Olive
Avocado
Ascophyllum nodosum
Alpha-Lipoic Acid
Astragaloside
anthocyanidins
Adzuki bean
Ampelopsin
Algal protein
Arjunic Acid
Alliin
anthocyanosides
Alisma
Argan nut oil
Arginine silicate
Arjunolic acid
Astragalin
Black Seed
Broussonetia
Brutieridin
Breadnut
Brown Algae
Brassica
Bayleaf
Bok Choy
Baicalein
Bael
Betanin
Bauhinia
Brazil nut
Barbasco
Bombax
Borassus aethiopum
Blue-Green Alage
banana
Baicalin
Buckwheat
Bassia scoparia
Bignay
Bottle gourd
Chia seed
Caffeic Acid
Camellia sinensis
Chinese Silkvine
Cowpea
California chia
Cyanobacteria
Catalpol
Cod Liver Oil
Chive
chlorogenic acid
Chinese Fleeceflower
Cantaloupe
Chlorophytum
Cruciferous
Cyclanthera pedata
Capers
Coconut Water
Chocolate
Chinese Ligustrum berry
C-Phycocyanin
Cha de bugre
Cherimoya
Crocetin
Carambola
Cassava
Clerodendrum indicum
Currant
Danshen
Daidzein
Dragon Fruit
Date
epicatechin
Eriocitrin
eggplant
Emblicanin
Eicosapentaenoic Acid
Eucommia ulmoides
Ecklonia
Fig
Fiber
Flavonones
Flammulina velutipes
Glycine
Isoflavones
Lotus
Milk Protein
Mistletoe
Prickly Pear Cactus
Quinoa Protein
Soy Protein
Sandalwood
Squash
walnut
Zucchini
Other health conditions supported by grape
Alzheimer's DiseaseArteriosclerosis
Cancer (prevention)
Cardiovascular Disease
Cellulite
Chemotherapy (reducing side effects)
Cholesterol (high)
Cholesterol (low)
Circulation (poor)
Circulation (to the brain)
Colds (general)
Colds (prevention)
Colds (with fever)
Congestion (bronchial)
Congestion (lungs)
Constipation (children)
Convalescence
Cough (general)
Cough (spastic)
Debility
Dementia
Diabetes
Diabetic Retinopathy
Fatty Liver Disease
Free Radical Damage
Gastritis
Gingivitis
Hypertension
Inflammation
Memory and Brain Function
Phlebitis
Triglycerides (high)
Ulcers
Wrinkles
Products containing grape
Vitabase
Active Man's Formula
Pure Encapsulations
Athletic Nutrients
Douglas Laboratories
Berberine Balance
Designs For Health
BergaVin™ 60 capsules
Vitabase
Bilberry Extract Plus
Metagenics
Ceralin® Forte
Vitabase
Cholesterol Support
Pure Encapsulations
CurcumaSorb Mind
Designs For Health
Detox Antiox™
Integrative Therapeutics
Detoxication Factors
Integrative Therapeutics
Detoxication Factors
Designs For Health
Detoxification Support Packets
Pure Encapsulations
DopaPlus
Integrative Therapeutics
EHB
Designs For Health
EssentiaGreens™
Douglas Laboratories
Glucosamine + MSM Forte ™
Douglas Laboratories
Glucosamine Plus ™
Pure Encapsulations
Grape Pip 500 mg
Vitabase
Grape Seed Extract
Thorne
Grape Seed Extract O.P.C.-100
Designs For Health
Grape Seed Supreme™
Douglas Laboratories
Hair Growth+
Pure Encapsulations
Hair/Skin/Nails Ultra
Designs For Health
HTN Supreme™
Douglas Laboratories
Juvenon Pro Cognitive
Klean Athlete
Klean Focus®
Vitabase
Life's Essentials Plus
Pure Encapsulations
Macular Support Formula
Pure Encapsulations
Macular Support Formula
Thorne
MediClear Plus
Douglas Laboratories
Optimized Curcumin With Neurophenol™
Designs For Health
PaleoCleanse Plus™
Designs For Health
PaleoCleanse Plus™
Designs For Health
PaleoCleanse Plus™ Detox Program
Designs For Health
PaleoCleanse Plus™Chocolate Detox Kit
Designs For Health
PaleoGreens®
Designs For Health
PaleoGreens®
Designs For Health
PaleoReds®
Designs For Health
PhytoBiome™
Metagenics
PhytoMulti™ Multivitamin
Metagenics
PhytoMulti With Iron
Metagenics
PhytoMulti Without Iron
Metagenics
PhytoMultivitamin
Designs For Health
Plant Protein Cleanse Plus™ 570g
Pure Encapsulations
Polyphenol Nutrients
Pure Encapsulations
Polyphenol Nutrients
Designs For Health
Primal Multi™
Pure Encapsulations
Resveratrol Extra
Pure Encapsulations
Resveratrol Extra
Integrative Therapeutics
Resveratrol Ultra HP 175mg
Designs For Health
Senolytic Synergy
Designs For Health
Ultimate Antiox Full Spectrum
Douglas Laboratories
Ultra Benfotiamine
Douglas Laboratories
Ultra Preventive
Douglas Laboratories
Ultra Preventive
Douglas Laboratories
Ultra Preventive ®-EZ Swallow
Douglas Laboratories
Ultra Preventive® X
Pure Encapsulations
Ultra Pure Pack
Pure Encapsulations
Uric Acid Formula
Douglas Laboratories
Uro-Pro ®
Pure Encapsulations
Vascular Relax
Designs For Health
Vessel Forte™
Vitabase
Vision Support
Metagenics
Wellness Essentials Active Daily Packs
Metagenics
Wellness Essentials Brain Health Daily Packs
Metagenics
Wellness Essentials® Daily Packs
Metagenics
Wellness Essentials Healthy Balance Daily Packs
Metagenics
Wellness Essentials Men's Vitality Daily Packs
Metagenics
Wellness Essentials Women's Daily Packs
Metagenics
Wellness Essentials Women's Prime Daily Packs
Pure Encapsulations
Women's Nutrients