Evidence supporting the use of: Isoflavone (unspecified)
For the health condition: Hypertension

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Isoflavones, particularly those derived from soy (such as genistein and daidzein), have been investigated for their potential effects on blood pressure and cardiovascular health. Several clinical trials and meta-analyses have evaluated the impact of isoflavone supplementation or high-soy diets on hypertension. Some studies suggest that isoflavones may exert modest blood pressure-lowering effects, particularly in postmenopausal women or individuals with pre-existing hypertension. The proposed mechanisms include improved endothelial function, increased nitric oxide production, and antioxidant activity.

However, the effect sizes reported are generally small and sometimes inconsistent. For example, a 2021 meta-analysis in Phytomedicine found a statistically significant, but clinically modest, reduction in both systolic and diastolic blood pressure with isoflavone supplementation. Other systematic reviews have echoed these findings, noting that while there may be some benefit, the evidence is not robust and the clinical significance is debatable. In addition, there is no strong tradition in herbal or folk medicine specifically linking isoflavones to the treatment of hypertension.

Overall, while there is some scientific evidence supporting a minor benefit of isoflavones for hypertension, the quality and magnitude of evidence are limited. Isoflavones are not considered a primary or stand-alone therapy for hypertension, but may contribute as part of a broader dietary approach.

More about isoflavone (unspecified)
More about Hypertension

Other ingredients used for Hypertension

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Products containing isoflavone (unspecified)

We currently have no products on Vitabase that contain this ingredient.