Evidence supporting the use of: Lactium casein decapeptide
For the health condition: Hypertension

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Lactium, a proprietary casein-derived decapeptide (αS1-casein hydrolysate), is promoted for its calming and stress-reducing effects. Its potential use in supporting or treating hypertension is based on scientific evidence, though the strength of this evidence is moderate. Several clinical studies and animal experiments have suggested that bioactive peptides derived from milk proteins, including Lactium, can exert antihypertensive effects primarily through the inhibition of angiotensin-converting enzyme (ACE), a key enzyme involved in blood pressure regulation. By inhibiting ACE, these peptides may help reduce vasoconstriction and lower blood pressure.

One notable human study (Mizuno et al., 2004, European Journal of Clinical Nutrition) demonstrated a modest but statistically significant reduction in systolic and diastolic blood pressure in mildly hypertensive subjects after supplementation with a casein hydrolysate containing Lactium. Other studies have found similar results, though the blood pressure-lowering effect appears to be modest compared to established antihypertensive medications. The mechanism is thought to be similar to that of ACE-inhibitor drugs, though with a milder effect and fewer side effects.

Despite these findings, the overall body of evidence is still limited, with relatively small sample sizes and short intervention periods. Therefore, while there is scientific validation for the use of Lactium casein decapeptide in supporting blood pressure management, it should be considered as an adjunct rather than a replacement for standard hypertension therapies. Further large-scale, long-term studies are needed to confirm its efficacy and establish clinical guidelines.

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Other ingredients used for Hypertension

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beta caryophyllene
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black currant
black garlic
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cauliflower
celery
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chia seed
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chlorella
chokeberry
cinnamon
citrus bioflavonoids
citrus sinensis (proprietary)
coenzyme Q10 (CoQ10)
coleus forskohlii
collard
cucumber
daidzin
diallyl disulfide (DADS)
diallyl trisulfide (DATS)
melon
eleuthero
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish oil
fish protein
flaxseed
forskohlii root
fruit and vegetable blend (proprietary)
gooseberry
gotu kola
grape
green tea
greens blend (proprietary)
hawthorn
hesperetin
hesperidin
hibiscus
jujube
kale
kudzu
l-arginine
l-citrulline
l-taurine
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lactobacillus helveticus
lentinula edodes mycelia
linoleic acid (LA)
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marine lipid
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Other health conditions supported by lactium casein decapeptide

Anxiety
Anxiety Disorders
Depression
Hypertension
Insomnia
Stress

Products containing lactium casein decapeptide

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