Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Quercetin is a flavonoid found in various fruits, vegetables, and plants, and its potential health benefits have been widely studied. Regarding hypertension, there is emerging scientific evidence suggesting that quercetin supplementation may help reduce blood pressure, particularly in individuals with elevated levels. Several randomized controlled trials (RCTs) and meta-analyses have investigated this effect. For instance, a 2020 meta-analysis published in the journal Phytotherapy Research reviewed 17 RCTs and concluded that quercetin supplementation, especially at doses of 500 mg per day or higher, resulted in modest but statistically significant reductions in both systolic and diastolic blood pressure in hypertensive and prehypertensive adults. The proposed mechanisms include antioxidant activity, improvement of endothelial function, and inhibition of angiotensin-converting enzyme (ACE), all of which can contribute to vascular relaxation and reduced blood pressure.

However, while the evidence is promising, it is not yet robust enough to recommend quercetin as a sole or primary treatment for hypertension. Most studies are of short duration, involve relatively small sample sizes, and sometimes yield inconsistent results. Larger, longer-term studies are needed to confirm efficacy and establish optimal dosing. Nonetheless, current research justifies the use of quercetin as a potential adjunctive supplement for blood pressure management, especially when combined with lifestyle modifications and/or conventional therapy.

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Other ingredients used for Hypertension

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