Evidence supporting the use of: Catecholamine
For the health condition: Hypotension

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Catecholamines, including agents such as epinephrine, norepinephrine, and dopamine, are well-established in the scientific and medical literature as primary treatments for hypotension, especially in acute and critical care settings. Their use is extensively validated by numerous clinical trials and their mechanisms of action are well understood. Catecholamines exert their effects by stimulating adrenergic receptors, leading to increased vascular tone (vasoconstriction), enhanced cardiac contractility, and elevated heart rate, all of which contribute to a rise in blood pressure. Current guidelines from organizations such as the American Heart Association and the European Society of Intensive Care Medicine recommend catecholamines for the management of hypotension, particularly in the context of shock (septic, cardiogenic, or anaphylactic shock). For example, norepinephrine is considered the first-line agent for septic shock due to its potent vasopressor activity and favorable safety profile compared to other agents. The efficacy of catecholamines in treating hypotension is supported by robust randomized controlled trials, systematic reviews, and decades of clinical use. Their use is routine in emergency medicine, intensive care, and anesthesia. Thus, the use of catecholamines for hypotension is not only scientifically validated but also forms a cornerstone of modern resuscitative therapy.

More about Catecholamine
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Products containing Catecholamine

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