Evidence supporting the use of: L-tyrosine
For the body system: Hypothalamus

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

L-tyrosine is an amino acid that serves as a precursor to several important neurotransmitters, including dopamine, norepinephrine, and epinephrine. These neurotransmitters play a critical role in the function of the hypothalamus, which regulates stress response, mood, and other hormonal activities. Some scientific studies have investigated l-tyrosine supplementation for its effects on cognitive performance and stress adaptation, particularly under conditions of acute stress or sleep deprivation. These studies suggest that supplemental l-tyrosine may help maintain cognitive function and mood during short-term physical or psychological stress, which involves hypothalamic activity.

However, while there is mechanistic plausibility and some experimental data supporting l-tyrosine’s impact on hypothalamic-related functions, the evidence remains limited and mixed. Most research focuses on stress and cognitive performance rather than direct hypothalamic health or function. Large-scale, long-term clinical trials specifically examining l-tyrosine’s effects on the hypothalamus are lacking. Thus, while the use of l-tyrosine to support hypothalamic functions is scientifically plausible and somewhat supported by preliminary research, the overall quality and quantity of evidence is low, justifying a modest evidence rating.

More about l-tyrosine
More about Hypothalamus

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