Evidence supporting the use of: Siberian ginseng
For the body system: Hypothalamus

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Siberian ginseng (Eleutherococcus senticosus), also known as eleuthero, has a long history of use in traditional medicine, particularly in Russia and China. It is categorized as an "adaptogen," a class of herbs reputed to help the body resist physical, environmental, and emotional stressors by supporting various physiological systems, including the hypothalamus-pituitary-adrenal (HPA) axis. The hypothalamus plays a central role in regulating the stress response, and Siberian ginseng is traditionally believed to enhance the body's resilience to stress by modulating this system.

Scientific evidence supporting the use of Siberian ginseng specifically for hypothalamus support is limited. Most research focuses on its general adaptogenic effects, fatigue reduction, and enhancement of mental and physical performance. Some animal and in vitro studies suggest that eleuthero extracts may influence stress hormones regulated by the HPA axis, but human trials are scarce and results are inconclusive. The evidence base is not robust enough to confirm direct, specific support for the hypothalamus itself. Thus, while traditional use is well-established, scientific validation for hypothalamic support remains preliminary.

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