Evidence supporting the use of: Tyrosine
For the body system: Hypothalamus

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Tyrosine is an amino acid that serves as a precursor for several important neurotransmitters, including dopamine, norepinephrine, and epinephrine. These neurotransmitters play key roles in the body’s response to stress, many of which are regulated by the hypothalamus-pituitary-adrenal (HPA) axis. Scientific studies have investigated L-tyrosine supplementation for its potential to support cognitive and physiological function during acute stress, including cold, sleep deprivation, or multitasking, which are conditions that can activate the hypothalamus.

Several small human studies suggest that tyrosine supplementation may help maintain cognitive performance and attenuate decreases in working memory and alertness during periods of acute stress. The proposed mechanism is that tyrosine provides additional substrate for catecholamine synthesis in the brain, which may be beneficial when demand for these neurotransmitters is high. However, these effects are generally modest, and not all studies report significant benefits. Importantly, there is limited direct evidence that tyrosine supplementation has a measurable or significant effect specifically on the hypothalamus as a body system or on its long-term health.

In summary, while there is some scientific rationale and limited evidence supporting the use of tyrosine to help buffer acute stress responses (processes in which the hypothalamus is involved), the overall evidence remains preliminary. Tyrosine is not widely recognized as a hypothalamus-targeted supplement, and more research is needed to clarify its direct benefits for hypothalamic function.

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Products containing Tyrosine

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