Evidence supporting the use of: Selenium ascorbate
For the health condition: Hypothyroid

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Selenium ascorbate combines selenium, an essential trace element, with ascorbic acid (vitamin C). Research indicates that selenium supplementation alone can support thyroid health, especially in cases of hypothyroidism related to autoimmune thyroiditis (Hashimoto’s thyroiditis). Selenium is a critical component of selenoproteins, such as glutathione peroxidase and iodothyronine deiodinases, which play key roles in protecting the thyroid gland from oxidative damage and in the conversion of thyroxine (T4) to the more active triiodothyronine (T3).

Several clinical trials and meta-analyses suggest that selenium supplementation may reduce thyroid peroxidase antibody (TPOAb) levels and modestly improve thyroid function in autoimmune hypothyroidism. However, the benefit is generally modest, and not all studies show a positive effect. The combination with ascorbic acid (vitamin C) is less well-studied; vitamin C is included primarily for its antioxidant properties, which may theoretically further reduce oxidative stress in the thyroid. There is limited direct evidence on the effectiveness of selenium ascorbate (the combined compound) as opposed to selenium alone for hypothyroid conditions.

In summary, there is scientific evidence supporting selenium's role in thyroid health and hypothyroidism, especially of autoimmune origin, but the clinical benefit is moderate (rated 3/5), and evidence for selenium ascorbate specifically is limited. Selenium supplementation should not replace conventional thyroid hormone therapy and should be used with caution due to potential toxicity at higher doses.

More about Selenium ascorbate
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Other health conditions supported by Selenium ascorbate

Cardiovascular Disease
Hypothyroid

Products containing Selenium ascorbate

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