Evidence supporting the use of: Vitamin D (mixed)
For the health condition: Hypothyroid

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin D has garnered scientific interest in relation to hypothyroidism, particularly autoimmune hypothyroidism such as Hashimoto’s thyroiditis. Several observational studies have reported that individuals with hypothyroidism, especially Hashimoto’s thyroiditis, often exhibit lower serum vitamin D levels compared to healthy controls. Some research suggests that vitamin D deficiency may be associated with increased thyroid antibody levels and greater risk or severity of autoimmune thyroid disorders. However, this association does not establish causality, and it remains unclear whether vitamin D deficiency contributes to the development or progression of hypothyroidism or is simply a consequence of autoimmune disease or other factors.

Interventional studies investigating whether vitamin D supplementation improves thyroid function or reduces thyroid antibodies in hypothyroid patients have yielded mixed results. Some small-scale trials suggest modest decreases in thyroid antibody titers with vitamin D supplementation, but most do not demonstrate substantial improvements in thyroid hormone levels or clinical outcomes. Major guidelines do not recommend vitamin D supplementation specifically for the treatment of hypothyroidism unless there is a documented deficiency.

In summary, while there is scientific rationale and some evidence linking low vitamin D levels to hypothyroidism, the strength of evidence for using vitamin D as a treatment for hypothyroidism is limited. Its use is justified primarily in the context of correcting a deficiency rather than as a direct therapy for hypothyroid disease.

More about Vitamin D (mixed)
More about Hypothyroid

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