Evidence supporting the use of: Chlorine
For the health condition: Impetigo

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Chlorine, typically in the form of diluted sodium hypochlorite (bleach) baths, is used as an adjunctive therapy for impetigo, especially in cases caused by Staphylococcus aureus or Streptococcus pyogenes. The rationale is based on chlorine’s well-established broad-spectrum antimicrobial properties. Scientific studies, including randomized controlled trials and systematic reviews, have evaluated the efficacy of dilute bleach baths in reducing bacterial colonization and improving outcomes in various skin infections, particularly atopic dermatitis with secondary infection, and to some extent impetigo.

A 2011 randomized controlled trial (Huang et al., Pediatrics) found that twice-weekly bleach baths combined with intranasal mupirocin reduced eczema severity and S. aureus colonization. While not specific to impetigo, these findings have influenced practice. The British Association of Dermatologists and NICE guidelines suggest dilute bleach baths as an option for recurrent or widespread impetigo, particularly when conventional antibiotic treatments are not effective or feasible. However, direct evidence for chlorine’s efficacy specifically in impetigo is limited, and most recommendations are extrapolated from studies on other staphylococcal skin infections.

In summary, the use of chlorine (sodium hypochlorite) for impetigo is supported by scientific evidence, though the strength of that evidence is moderate and largely indirect. It may be considered in specific clinical scenarios, but it is not a first-line treatment.

More about Chlorine
More about Impetigo

Other health conditions supported by Chlorine

Abrasions
Cholera
Cuts
Gangrene
Impetigo
Infection
Infection (bacterial)

Products containing Chlorine

We currently have no products on Vitabase that contain this ingredient.