Evidence supporting the use of: Bicarbonate (unspecified)
For the health condition: Indigestion

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Bicarbonate, commonly in the form of sodium bicarbonate (baking soda), is scientifically validated as a treatment for indigestion, particularly symptoms related to excess stomach acid such as heartburn or acid indigestion. Its use dates back over a century, and it is an ingredient in many over-the-counter antacid preparations. The mechanism of action is straightforward: bicarbonate acts as a base, neutralizing gastric hydrochloric acid to form salt, water, and carbon dioxide, thereby raising gastric pH and providing rapid symptomatic relief from acid-related discomfort.

Clinical guidelines and pharmacological references (such as the British National Formulary and the U.S. FDA monographs) recognize sodium bicarbonate as an effective, fast-acting antacid. Its efficacy in providing short-term relief for acid indigestion has been confirmed in controlled studies and is widely accepted in medical practice. However, its use is generally recommended for occasional, not chronic, indigestion due to potential adverse effects, such as metabolic alkalosis and sodium overload, especially with excessive or prolonged use.

Despite newer antacid and acid-suppressing medications now being available, bicarbonate remains a validated option for immediate, short-term symptom management. It should be used with caution in individuals with cardiovascular, renal, or hepatic conditions due to the high sodium content. In summary, bicarbonate’s use for indigestion is both scientifically supported and well-established in clinical practice, earning it a high evidence rating for this indication.

More about Bicarbonate (unspecified)
More about Indigestion

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Products containing Bicarbonate (unspecified)

We currently have no products on Vitabase that contain this ingredient.