Evidence supporting the use of: Licorice root
For the health condition: Indigestion

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Licorice root (Glycyrrhiza glabra) has a long history of use in traditional medicine systems, particularly in Chinese and Ayurvedic medicine, for supporting digestive health and relieving symptoms of indigestion. The root contains several bioactive compounds, such as glycyrrhizin and flavonoids, which are believed to contribute to its therapeutic effects.

Modern scientific research provides some support for the use of licorice root in the management of indigestion and related gastrointestinal complaints. Studies have shown that deglycyrrhizinated licorice (DGL), a form of licorice with the glycyrrhizin component removed to reduce side effects, may help soothe the mucosal lining of the stomach and esophagus. Randomized controlled trials have found that DGL can be effective in reducing symptoms of dyspepsia (indigestion), such as bloating, heartburn, and discomfort. The proposed mechanisms include increased mucus production and enhanced mucosal defense, which may help protect against stomach acid and promote healing of the gastrointestinal lining.

Despite these findings, the overall quality of evidence is moderate, and more high-quality clinical trials are needed to confirm efficacy and establish optimal dosing. It is also important to note that whole licorice root can cause significant side effects, such as hypertension and electrolyte imbalance, especially with prolonged use, so DGL preparations are generally preferred for digestive support.

More about licorice root
More about Indigestion

Other ingredients used for Indigestion

cutch
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Activated charcoal
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Aloe vera
alpha-galactosidase
amylase
green chiretta
apple
apricot
artichoke
bamboo
benegut perilla (proprietary)
betel
Bifidobacterium bifidum
Bifidobacterium infantis
Bifidobacterium longum
black pepper
radish
rice
calcium
cassia bark
chamomile
chen pi
chloride
citrus sinensis (proprietary)
cucumber
turmeric
curcumin
dandelion
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exo-peptidase
fennel
fenugreek
fruit and vegetable blend (proprietary)
gentian root
ginger
glucomannan
green banana
HCL
quassia
jujube
kudzu
Lactobacillus gasseri
Lactobacillus lactis
lactiplantibacillus plantarum
licorice root
lipase
liquid liver fractions
lovage
Marshmallow
Methylmethionine sulfonium chloride (vitamin U)
Mint
orange
oregon grape
ox bile
pancreatin
papain
Peppermint
pepsin
plum fruit
psyllium
quail egg
rhubarb root
schizonepeta
slippery elm bark
spearmint leaf
Watermelon
Xylanase
bentonite
cascara sagrada
oryza
tangerine
hyssop
cardamom
atractylodes
capsicum
Indian bael
alpinia galangal
Clerodendrum indicum
ferula assafoetida
Hedychium spicatum
inula racemosa
anise
punarnava
holarrhena antidysenterica
Fumaria parviflora
blessed thistle
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bile salt
prickly ash
elecampane
root tuber
chrysanthemum
juniper berries
flowering quince
dogwood
dioscorea
sweetgums
queen of the meadow
caraway
anemarrhena asphodeloides
peach
Wood betony
horehound
Sichuan pepper
Alginic acid
sea salt
Alcohol
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apple cider vinegar
Actinidin
Agastache
ambergris
Angelica
Agrimony
Amomum
Asarum heterotropoides
Alchemilla
asafoetida
Agarwood
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Appleblossom Cassia
Asam gelugor
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arrowroot
Areca
Agrimonia pilosa
antifoam agent
Amor seco
Aniseed myrtle
Arani
Arisaema
Asarum sieboldii
atractylone
betony
buttermilk
butter
blue flag
Baliospermum
blackthorn
Broussonetia
bicarbonate
bayleaf
belleric myrobalan
blackbrush
bistort
big quaking grass
Bougainvillea
bael
butternut
boldo
black gram
bile
black salt
Bombax
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bitter principals
banana
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bottle gourd
cumin
centaury
carqueja
chervil
coriander
chive
cape aloe
Centaurium erythraea
citron
cantaloupe
Chlorophytum
carvone
Cymbopogon martini
coca
Campylandra fimbriata
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colombo
copalchi
cubeb
carob
chirata
Chaenomeles lagenaria
Carlina
calamus
chestnut
colocynth
cola nut
Clerodendrum indicum
dense fruit dittany
dextrin
dragonhead
dill
dianthrone
Dolichos
Dichrostachys glomerata
English horsemint
enzyme blend
elephant\'s head
fig
fumitory
flat-stem milk-vetch
fernbush
false calumba
four-leaved grass
goldthread
gentian
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Gentianopsis barbata
grains of paradise
garden cress
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Galbanum
Gentiana manshurica
Heartsease
Himalayan salt
Hygrophila
Horsemint
Jicama
Jurubeba
Jalap
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Khella
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Kukicha
kola nut
karaya gum
Kefir
kuding tea
lemon balm
lime
Large-leaf gentian
Lactobacillus kefiri
Lesser speargrass
Lilium polyphyllum
linden
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labrador tea
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Lysimachia
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Mentha haplocalyx
mandarin
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Mucilage
mace
malt
Mountain mahogany
Mesquite
Microtea debilis
Morning glory
Meadowsweet
Nardostachys
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Oroxylum indicum
Orchis latifolia
Orris
Operculina turpethum
Osmanthus
Parsnip
Piperine
Palmyra
Piper chaba
Pulsatilla
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probiotics
Piper retrofractum
polydimethylsiloxane
pointed gourd
Prickly Pear Cactus
Polygonatum
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Patrinia
potash
quince
rue
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Scabrous Gentian
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Other health conditions supported by licorice root

Abdominal Pain
Abrasions
Abscesses
Acid Indigestion
Acne
Addictions (general remedies for)
Addictions (tobacco smoking or chewing)
Addison's Disease
Adenitis
Adrenal Fatigue
Afterbirth Pain
Age Spots
Allergies (respiratory)
Amenorrhea
Anal Fistula or Fissure
Anemia
Appetite (deficient)
Asthma
Autoimmune Disorders
Bronchitis
Canker Sores
Chemotherapy (reducing side effects)
Chicken Pox
Cholera
Chronic Obstructive Pulmonary Disorder
Cirrhosis of the Liver
Cold Sores
Colds (antiviral)
Colds (decongestant)
Colds (general)
Colds (prevention)
Colds (with fever)
Colic (adults)
Colic (children)
Colitis
Colon (atonic)
Colon (spastic)
Congestion
Congestion (bronchial)
Congestion (lungs)
Congestion (lymphatic)
Congestion (sinus)
Constipation (adults)
Contagious Diseases
Convalescence
Cough (damp)
Cough (dry)
Cough (general)
Cough (spastic)
Cramps (menstrual)
Crohn's Disease
Croup
Cushing's Disease
Cytomealovirus
Dyspepsia
Eczema
Emphysema
Endometriosis
Enteritis
Epstein Barr Virus
Estrogen (low)
Fatty Liver Disease
Fever
Fibrosis
Gall Bladder (sluggish or removed)
Gall Stones
Gas and Bloating
Gastritis
Gingivitis
Glands (swollen lymph)
Goiter
Gonorrhea
Gout
Grave's Disease
Hair (loss or thinning)
Hair Care (general)
Halitosis
Hangover
Headache (general)
Headache (sinus)
Headache (tension)
Heart (weakness)
Hemorrhoids
Hepatitis
Hernias
Herpes
Hiatal Hernia
Hiccups
Hot Flashes
Hypotension
Hypothyroid
Impetigo
Indigestion
Infection
Infection (bacterial)
Infection (viral)
Inflammation
Inflammatory Bowel Disorders
Influenza
Injuries
Itching
Itching Ears
Jaundice (adults)
Jock Itch
Kidney Infection
Laryngitis
Leaky Gut Syndrome
Leprosy
Lesions
Leucorrhea
Liver Detoxification
Lungs (fluid in)
Lyme Disease
Lymph Nodes or Glands (swollen)
Malaria
Mastitis
Measles
Menopause
Menorrhagia
Menstrual Irregularity
Menstruation (scant)
Mental Illness
Metabolic Syndrome
Mononucleosis
Mood Swings
Morning Sickness
Mumps
Nausea and Vomiting
Nephritis
Nervous Exhaustion
Nervousness
Night Sweating
Nocturnal Emission
Oral Surgery
Ovarian Pain
Overacidity
Pertussis
Pleurisy
PMS (general)
Pneumonia
Poison Ivy or Oak
Rashes and Hives
Rosacea
Sore Throat
Ulcers