Evidence supporting the use of: Peppermint oil
For the health condition: Indigestion

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Peppermint Oil for Indigestion: Scientific Evidence

Peppermint oil has both a long history of traditional use and a significant body of scientific evidence supporting its role in managing indigestion, particularly functional dyspepsia and symptoms related to irritable bowel syndrome (IBS). The primary mechanism attributed to peppermint oil is its antispasmodic effect on the smooth muscles of the gastrointestinal (GI) tract. This effect is chiefly due to menthol, the major constituent of peppermint oil, which blocks calcium channels in GI smooth muscle, resulting in muscle relaxation and reduced spasms.

Randomized controlled trials and meta-analyses have shown that enteric-coated peppermint oil capsules can significantly improve symptoms of indigestion, including abdominal pain, bloating, and discomfort. A 2019 meta-analysis published in BMC Complementary Medicine and Therapies reported that peppermint oil was more effective than placebo in relieving global symptoms of functional dyspepsia. The enteric coating is crucial, as it ensures the oil is released in the intestines rather than the stomach, minimizing the risk of heartburn or gastroesophageal reflux.

While most studies have focused on IBS, overlap with functional dyspepsia symptoms means peppermint oil is often used for general indigestion as well. Side effects are generally mild but can include heartburn or allergic reactions in sensitive individuals. In summary, the use of peppermint oil for indigestion is supported by both tradition and robust scientific evidence, meriting a high evidence rating.

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