Evidence supporting the use of: Piperin
For the health condition: Indigestion

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Piperine, the active compound found in black pepper (Piper nigrum), has a long history of use in traditional medicine systems such as Ayurveda and Traditional Chinese Medicine for a variety of gastrointestinal complaints, including indigestion (also known as dyspepsia). Traditional texts and ethnobotanical records describe black pepper and its extracts as “digestive stimulants,” believed to enhance appetite, promote secretion of digestive juices, and improve gastrointestinal motility.

However, direct scientific evidence supporting the efficacy of piperine for treating indigestion in humans is limited. Most modern research on piperine focuses on its bioenhancing properties—its ability to increase the absorption of other nutrients and drugs—rather than its direct effects on digestive symptoms. Some animal studies and in vitro research suggest that piperine can increase the activity of digestive enzymes and stimulate bile secretion, which could theoretically aid digestion. Nevertheless, robust clinical trials in humans specifically examining piperine’s effects on indigestion are lacking.

In summary, while piperine’s use for indigestion is well-documented in traditional medicine, scientific validation remains limited and primarily indirect. More research is needed to confirm its effectiveness and safety for this specific purpose in modern clinical practice.

More about Piperin
More about Indigestion

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Products containing Piperin

We currently have no products on Vitabase that contain this ingredient.