Evidence supporting the use of: Alantolactone
For the health condition: Infection

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Alantolactone is a sesquiterpene lactone compound primarily found in the roots of Inula helenium (elecampane). Its traditional use in herbal medicine has centered around respiratory ailments rather than infection specifically. However, recent years have seen an increase in scientific studies examining its antimicrobial properties.

In vitro studies have demonstrated that alantolactone exhibits antibacterial and antifungal activities. For example, research shows inhibitory effects against Staphylococcus aureus (including MRSA), Escherichia coli, and certain pathogenic fungi such as Candida albicans. The proposed mechanisms include disruption of microbial cell membranes, inhibition of biofilm formation, and interference with microbial enzyme systems.

Despite these promising laboratory results, there is a lack of high-quality clinical evidence in humans supporting the use of alantolactone for the treatment of infections. Most studies are preclinical, and there are no robust clinical trials evaluating efficacy, safety, or dosing in humans. Thus, while there is a scientific basis for potential antimicrobial effects, current evidence does not justify recommending alantolactone as a standalone treatment for infections in clinical practice. Further research, particularly human trials, is needed to establish its efficacy and safety profile.

More about Alantolactone
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Other ingredients used for Infection

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3-Phenyllactic Acid
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Abuta
Acacia
Acemannan
Aerva lanata
Agarikon Mushroom
Agastache
Agave
AHCC
Ajoene
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Alchornea
Alkylglycerols
Allicin
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Allyl sulfide
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amber
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Angelica
animal protein
annatto
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Aquilegia viridiflora
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astragalus
aucubin
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avens
babchi
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Bacillus
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bacteria
balsam
banyan
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barbary matrimony vine
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bayberry
bearberry
bee pollen
bee propolis
Beef liver
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benzyl isothiocyanate
Berberis (unspecified)
Bergenia
beta-glucan
betel
Bifidobacterium
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bignay
birch
bisabolene
bitter principals
black nightshade
black pepper
black root
black walnut
blackboard tree
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Blepharis
boneset
Borassus aethiopum
borassus palm
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calamus
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Products containing Alantolactone

We currently have no products on Vitabase that contain this ingredient.