Evidence supporting the use of: Alliin
For the health condition: Infection

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Alliin is a sulfur-containing compound found in garlic (Allium sativum). Its use to support or treat infections has scientific grounding, although the evidence is still preliminary and mostly based on laboratory and animal studies rather than large-scale human clinical trials. When garlic is crushed or chopped, alliin is converted by the enzyme alliinase into allicin, which has been shown to possess antimicrobial properties against a variety of bacteria, viruses, and fungi in vitro.

Several studies suggest that garlic extracts, which contain alliin and its derivatives, can inhibit the growth of pathogens such as Staphylococcus aureus, Escherichia coli, and Candida albicans. The proposed mechanisms include disruption of microbial cell membranes and inhibition of key enzymes involved in microbial metabolism. However, most of these studies are laboratory-based, and the translation of these effects to clinical efficacy in humans is uncertain. Limited clinical trials suggest a modest benefit of garlic preparations in reducing the incidence or duration of the common cold and other mild infections, but these findings are not robust or consistently replicated.

In summary, while there is scientific evidence supporting the antimicrobial activity of alliin-derived compounds from garlic, direct clinical evidence for alliin itself in treating infections is limited. More rigorous, controlled human studies are needed before alliin can be conclusively recommended for infection management.

More about Alliin
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Products containing Alliin

We currently have no products on Vitabase that contain this ingredient.